Actively Recruiting
Comparing the Effect of siSPARC Microneedle Patch Versus siSPARC+siLR4A Microneedle Patch on Post-surgical Scars
Led by National Skin Centre · Updated on 2024-06-24
50
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This randomized, double-blind controlled study aims to compare the effect on appearance of post- surgical scars between daily application of siSPARC microneedle patch versus siSPARC + siLR4A microneedle patches. These are patches comprising short microneedles embedded with hydrolysed RNA (siRNAs).
CONDITIONS
Official Title
Comparing the Effect of siSPARC Microneedle Patch Versus siSPARC+siLR4A Microneedle Patch on Post-surgical Scars
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult aged 21 to 75 years
- At least 2 weeks (+/- 7 days) after surgical operation with incision into the dermis
- Stitches have been removed after surgery
- Wound closure or union has been achieved
You will not qualify if you...
- Pregnant or lactating participant
- Wound infection present
- Unable or uncooperative to self-apply the patch
- Known allergy to patch ingredients (hyaluronic acid, siRNA, glue) or isopropyl alcohol
- Unable to provide personal informed consent (e.g., cognitive impairment)
AI-Screening
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Trial Site Locations
Total: 1 location
1
National Skin Centre
Singapore, Singapore, 308205
Actively Recruiting
Research Team
H
Hong Liang Tey
CONTACT
D
Delwyn Lim
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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