Actively Recruiting
Comparing the Efficacy of Surgery Staging and Image Staging of Locally Advanced Cervical Cancer
Led by Chongqing University Cancer Hospital · Updated on 2023-08-31
1956
Participants Needed
1
Research Sites
548 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study is a domestic multicenter, prospective, non-randomized controlled concurrent trial. It will be assessed whether surgery staging on locally advanced cervical cancer is superior to image staging for improving progression-free survival and overall survival.
CONDITIONS
Official Title
Comparing the Efficacy of Surgery Staging and Image Staging of Locally Advanced Cervical Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with good compliance who voluntarily signed informed consent
- Histopathology showing squamous cell carcinoma, adenocarcinoma, or adenosquamous cell carcinoma
- Cervical cancer stages IB3, IIA2, IIB to IVA according to FIGO2018
- ECOG performance score of 0 or 1
- Expected survival greater than 6 months
- Negative pregnancy test within seven days for women of childbearing age and use of contraception during the trial
You will not qualify if you...
- Active or uncontrolled severe infection
- Liver cirrhosis or other decompensated liver disease
- History of immune deficiency including HIV positive or congenital immunodeficiency
- Chronic renal insufficiency or renal failure
- Other malignancies diagnosed or requiring treatment within five years
- Myocardial infarction, severe arrhythmia, or congestive heart failure grade 2 or higher
- Positive para-aortic lymph nodes on CT/MRI/PET/CT
- History of pelvic artery embolization
- History of pelvic radiotherapy
- History of partial or radical hysterectomy
- Severe allergic reaction to platinum drugs
- Use of drugs impairing liver or kidney function such as tuberculosis treatments
- Inability to understand the research or refusal to sign informed consent
- Other serious diseases or conditions that endanger health or interfere with the trial
AI-Screening
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Trial Site Locations
Total: 1 location
1
Chongqing University Cancer Hospital
Chongqing, Chongqing Municipality, China, 400000
Actively Recruiting
Research Team
D
Dongling Zou, M.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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