Actively Recruiting
Comparing How Burn Wounds and Scars Heal in Children Using Chitosan and Silver Dressings
Led by Miloš Potkonjak · Updated on 2025-09-04
40
Participants Needed
1
Research Sites
114 weeks
Total Duration
On this page
Sponsors
M
Miloš Potkonjak
Lead Sponsor
G
General Hospital of Novo mesto
Collaborating Sponsor
AI-Summary
What this Trial Is About
Burns are among the most common types of trauma worldwide, ranking fourth after traffic accidents, falls, and violence, and account for an estimated 265,000 deaths annually (WHO). Most burn injuries result from heat exposure, though other causes include friction, chemicals, and electricity. Effective burn treatment aims to promote wound healing by supporting tissue regeneration and maintaining optimal conditions such as moisture, oxygenation, and low bacterial load. In Slovenia and across Europe, silver-based dressings are commonly used for burn care. While they are known to support wound healing, their effectiveness in reducing scar formation remains unclear. Chitosan-based hydrogels, by contrast, offer promising benefits due to their natural biocompatibility, antibacterial action, and support for tissue repair, though clinical data are still limited. This study aims to compare the effectiveness of chitosan-based and silver-based dressings in burn wound healing, focusing on healing time, scar formation, cost-efficiency, and patient experience. Scar outcomes will be assessed using the validated POSAS (Patient and Observer Scar Assessment Scale).
CONDITIONS
Official Title
Comparing How Burn Wounds and Scars Heal in Children Using Chitosan and Silver Dressings
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 6 months and 17 years old
- First or second-degree superficial burn not requiring excision and grafting
- Burn covers less than 20% of total body surface area
- Admission within 72 hours of burn injury
- Burnshield���Dressing used as first therapy for 48 hours
- Clean, non-infected wound as diagnosed by a physician
- Informed consent given by patient or caregiver
You will not qualify if you...
- Burns caused by electrical, chemical, or frostbite injuries
- Diabetes mellitus
- Significant heart, lung, or kidney problems
- Severe blood diseases, cancer, or weak immune system
- Wounds that are contaminated or infected
- Systemic inflammatory response syndrome (SIRS) or sepsis
- Moderate or severe respiratory tract or lung burns
- Prior treatments like debridement or certain topical agents
- Pregnancy or breastfeeding
- Known allergy to the dressings or their components
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
General Hospital Novo mesto
Novo Mesto, Slovenia, 8000
Actively Recruiting
Research Team
M
Miloš Potkonjak, MD, surgeon
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here