Comparing Physiotherapy Plus One of Three Injection Treatments for Tennis Elbow Pain and Function

What this Trial Is About

Tennis elbow, a common musculoskeletal condition causing pain at the lateral epicondyle of the humerus, is mainly due to overuse of wrist extensor muscles. Treatments vary from oral medications and physiotherapy to injections, with surgery reserved for resistant cases. This research aims to clarify the best approach by comparing physiotherapy combined with three types of injections for pain relief and function improvement in tennis elbow patients. Participants will all receive a structured, class-based physiotherapy program while being randomly assigned to one of three injection groups a platelet-rich plasma PRP injection, a sodium hyaluronate with mannitol Ostenil Tendon injection, or a sham injection that penetrates the skin but delivers no therapeutic substance. Injections are administered under ultrasound guidance, and the study is designed as a double-blind, randomized controlled trial. Throughout the study, participants will complete questionnaires including pain scales and functional assessments at baseline, 3 months, and 12 months after treatment. They will keep a pain diary during the first 12 weeks and be monitored for medication use and recovery progress. The main outcome is the change in Quick Disabilities of the Arm, Shoulder and Hand QuickDASH score at 12 months, supplemented by other measures of pain, function, and quality of life, all conducted under blinded evaluation.

Comparing Injection Treatments for Tennis Elbow