Actively Recruiting
Comparing Numbing Techniques in Mohs Micrographic Surgery
Led by Abramson Cancer Center at Penn Medicine · Updated on 2026-01-29
150
Participants Needed
1
Research Sites
26 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study seeks to determine whether adjunct regional nerve blocks reduce pain and anxiety in adult patients undergoing Mohs micrographic surgery for face and scalp skin cancers. Participants will be randomized to one of two arms: (1) placebo regional nerve block with sterile normal saline or (2) adjunct regional nerve block with lidocaine. All patients receive local infiltration with lidocaine for complete anesthesia.
CONDITIONS
Official Title
Comparing Numbing Techniques in Mohs Micrographic Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 6518 years.
- Scheduled to undergo Mohs micrographic surgery.
- Lesions located on the face or scalp defined by specific anatomic boundaries.
- Tumor diameter plus anticipated stage 1 margin 652 cm or any tumor on the lip, nose, or eyelid.
- Ability to complete patient-reported outcome measures in English.
You will not qualify if you...
- Known allergy or contraindication to lidocaine or epinephrine.
- Chronic opioid use or pre-existing pain disorders affecting pain reporting.
- Scar tissue at local infiltration or nerve block site that may alter anesthetic effect.
- Concurrent multi-site Mohs procedure.
- Signs of infection at local infiltration or nerve block site.
- Inability to understand or complete pain and satisfaction assessments.
- Pregnant or breastfeeding.
- Use of sedatives or anxiolytics before the procedure.
AI-Screening
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Trial Site Locations
Total: 1 location
1
Perelman Center for Advanced Medicine
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
Research Team
K
Kaiyu Ma Clinical research regulatory specialist, PhD
CONTACT
C
Christopher Richter, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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