Actively Recruiting

Phase Not Applicable
Age: 18Years - 40Years
FEMALE
NCT07395934

Comparing PIEB and CEI for Labor Pain Relief

Led by Da Nang Family General Hospital · Updated on 2026-02-09

60

Participants Needed

1

Research Sites

56 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this randomized controlled trial is to compare the efficacy and safety of two epidural analgesia maintenance methods for labor pain relief: Programmed Intermittent Epidural Bolus (PIEB) and Continuous Epidural Infusion (CEI), both combined with Patient-Controlled Epidural Analgesia (PCEA). The study aims to evaluate which technique provides superior analgesia while minimizing anesthetic consumption and preserving maternal motor function. A total of 60 parturients at Family Hospital, Da Nang, will be randomly assigned to either the PIEB or CEI group. Outcomes including pain intensity (VAS scores), total drug consumption, maternal satisfaction, and neonatal Apgar scores will be assessed.

CONDITIONS

Official Title

Comparing PIEB and CEI for Labor Pain Relief

Who Can Participate

Age: 18Years - 40Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Parturients indicated for labor analgesia for vaginal delivery via epidural anesthesia.
  • Age from 18 to 40 years.
  • Physical status: ASA II.
  • Singleton pregnancy, full-term, vertex presentation in labor.
  • Indication for vaginal delivery.
  • No contraindications to epidural anesthesia.
  • Agreement to participate in the research and signed written informed consent.
Not Eligible

You will not qualify if you...

  • Contraindications to epidural analgesia.
  • History of allergy to local anesthetics (Ropivacaine) or opioids (Fentanyl).
  • High-risk pregnancies: Preeclampsia, placenta previa, placental abruption.
  • Fetal distress or fetal abnormalities.
  • Chronic use of analgesic drugs or neurological/psychiatric disorders.
  • Parturients who refuse to participate or request to withdraw from the research.

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Family General Hospital

Da Nang, Vietnam, 50000

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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