Actively Recruiting
Comparing Intravenous and Intrathecal Pethidine to Prevent Shivering After Spinal Anesthesia During Caesarean Section in Women Aged 20 to 40
Led by Alexandria University · Updated on 2025-01-15
86
Participants Needed
1
Research Sites
4 weeks
Total Duration
AI-Summary
What this Trial Is About
This trial focuses on females aged 20 to 40 years undergoing elective cesarean section under spinal anesthesia. It aims to compare two ways of giving pethidineintravenous IV and intrathecalto see which is better at preventing shivering after spinal anesthesia. Researchers also want to learn how these methods affect heart and blood pressure stability, nausea, vomiting, and sedation. Participants are randomly assigned to one of two groups. One group receives IV pethidine at 0.5 mgkg mixed in saline before surgery, while the other receives 0.2 mgkg pethidine injected into the spinal area along with bupivacaine. Spinal anesthesia will be administered using a needle between the lower back vertebrae. Patients will not be actively warmed during surgery, and medications like ephedrine and atropine will be given if blood pressure or heart rate drop. Room temperature will be controlled during the operation and recovery. Throughout the surgery and recovery, participants will be closely monitored for shivering using a standardized scale every 15 to 30 minutes. Vital signs like heart rate and blood pressure will be checked regularly, along with body temperature. Researchers will also record any nausea, vomiting, or sedation. The main outcomes measured are the frequency, start time, length, and severity of shivering. Secondary outcomes include heart and blood pressure stability and side effects. Monitoring continues for the first two hours after surgery.
CONDITIONS
Brief Title
Comparing Prophylactic Intravenous Pethidine and Intrathecal Pethidine in Preventing Post Spinal Shivering in Caesarean Section
Research Team
M
Mai A El-Sayed, Lecturer of Anesthesia
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