Actively Recruiting
Comparing Revisional Laparoscopic Roux-en-Y Gastric Bypass Versus Ringed Revisional Roux-en-Y Gastric Bypass After Laparoscopic Sleeve Gastrectomy
Led by General Committee of Teaching Hospitals and Institutes, Egypt · Updated on 2026-04-29
240
Participants Needed
1
Research Sites
258 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Obesity remains a major global health challenge, with rising prevalence and significant metabolic, cardiovascular, and gastrointestinal comorbidities. Laparoscopic sleeve gastrectomy (LSG) has emerged as the most widely performed bariatric procedure due to its technical simplicity and satisfactory short- to mid-term results. However, a proportion of patients experience suboptimal weight loss, recurrent weight gain, or both. In this study, patients with recurrent weight gain of maximum weight loss or suboptimal weight loss or both following sleeve gastrectomy were included. Suboptimal weight loss is defined as total weight loss (TWL) of less than 20% of the preoperative weight and/or excess weight loss (EWL) of less than 50%, measured at least 12-18 months after the primary sleeve gastrectomy. Recurrent weight gain after sleeve gastrectomy is defined as an increase of ≥20% of the maximum weight loss (from nadir weight) or an increase in BMI of \>5, measured at least 24 months after the primary procedure.
CONDITIONS
Official Title
Comparing Revisional Laparoscopic Roux-en-Y Gastric Bypass Versus Ringed Revisional Roux-en-Y Gastric Bypass After Laparoscopic Sleeve Gastrectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18-65 years
- Patients with recurrent weight gain or suboptimal weight loss at least 12-24 months after sleeve gastrectomy
- Eligible and fit for bariatric surgery
- Willing to provide informed consent and comply with follow-up
You will not qualify if you...
- Severe psychiatric disorders or uncontrolled substance abuse
- Pregnancy or planning pregnancy within 2 years after surgery
- Chronic steroid or immunosuppressive therapy
- Active cancer or history of gastrointestinal cancer
- Severe heart or lung disease preventing surgery
- Uncontrolled endocrine disorders except type 2 diabetes
- Unable to comply with follow-up or study requirements
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The surgical department of Medical Research Institute Hospital, Alexandria University
Alexandria, Alexandria Governorate, Egypt, 21531
Actively Recruiting
Research Team
M
Mohamed H Ashour, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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