Comparing Two Regional Blocks to Reduce Opioid Use After Lumbar Microdiscectomy Surgery
Led by Medipol University · Updated on 2026-07-27
90
Participants Needed
1
Research Sites
4 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are comparing two regional anesthesia techniques, the Thoracolumbar Interfascial Plane TLIP block and the Quadro Iliac Plane Block, for pain control after lumbar microdiscectomy surgery. This surgery treats herniated discs, and managing pain well after surgery is important to help patients recover early and avoid complications such as opioid dependence and respiratory problems. The study aims to see which block better reduces opioid use and related side effects.
Participants are randomly assigned to one of three groups one group receives standard pain control without any additional nerve block, the second group receives the TLIP block along with standard analgesia, and the third group receives the Quadro Iliac Plane Block plus standard analgesia. Both blocks are performed using ultrasound guidance after surgery but before the patient wakes up, with 20 mL of 0.25% bupivacaine injected at specific sites.
During the first 24 hours after surgery, researchers will monitor tramadol an opioid consumption, pain levels using the Numeric Rating Scale NRS, and opioid-related side effects such as nausea, vomiting, and respiratory depression. The study includes adults aged 18 to 80 years undergoing lumbar microdiscectomy and continues until the primary outcome is assessed. Participants recovery and pain management are closely observed to understand the effectiveness of these blocks compared to standard care.
CONDITIONS
Brief Title
Comparing Thoracolumbar Interfascial and Quadro Iliac Plane Blocks on Postoperative Opioid Use Following Lumbar Microsurgery
Research Team
B
Burak Ömür
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American Society of Anesthesiologists (ASA) physical status I to III
Scheduled for lumbar microdiscectomy surgery
You will not qualify if you...
Known allergy to local anesthetics
Any other significant drug allergies related to the study interventions
Pregnancy
Pre-existing psychiatric or neurological disorders
Inability to provide informed consent
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Treatment
Duration - First 24 hours after surgery
Participants receive either standard pain control, the Thoracolumbar Interfascial Plane block, or the Quadro Iliac Plane Block after lumbar microsurgery. The blocks are given under ultrasound guidance before waking up from surgery.
1 postoperative assessment
Follow-up
Duration - First 24 hours after surgery
Researchers monitor pain levels, opioid use, and side effects during the first 24 hours after surgery to evaluate pain management effectiveness.
Ongoing monitoring during hospital stay
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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Published Research Related To This Trial
Posterior Quadratus Lumborum Block or Thoracolumbar Interfascial Plane Block and Postoperative Analgesia after Spinal Surgery: A Randomized Controlled Trial.