Actively Recruiting
Comparing Three Rescue Bowel Preparation Regimens for Colonoscopy After Failed Cleansing
Led by Ospedale San Pio · Updated on 2026-05-14
220
Participants Needed
1
Research Sites
125 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn which rescue bowel preparation works best for adults who need a repeat colonoscopy after a previous bowel preparation did not clean the bowel well enough. The study will also look at how satisfied participants are with each preparation. The main questions it aims to answer are: * Which bowel preparation helps more participants achieve adequate bowel cleansing before repeat colonoscopy? * Which bowel preparation leads to better cleansing in different parts of the colon? * Which bowel preparation is better tolerated by participants? Researchers will compare 3 rescue bowel preparation regimens to see which one works best for repeat colonoscopy after a previous cleansing failure. Participants will: * be randomly assigned to 1 of 3 bowel preparation regimens * take one of the following regimens before repeat colonoscopy: * 4 liters of polyethylene glycol (PEG) plus 12 milligrams of bisacodyl * 1 liter of PEG plus ascorbic acid plus 10 milligrams of bisacodyl * 2 liters of PEG plus extra PEG taken over the 3 days before colonoscopy * undergo repeat colonoscopy * rate their satisfaction with the bowel preparation
CONDITIONS
Official Title
Comparing Three Rescue Bowel Preparation Regimens for Colonoscopy After Failed Cleansing
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years or older
- Prior inadequate bowel preparation (adequately performed) requiring repeat colonoscopy
- Scheduled to undergo repeat outpatient colonoscopy
- Ability to provide informed consent
You will not qualify if you...
- Age younger than 18 years
- Inability to provide informed consent
- Contraindication to any study bowel preparation regimen or colonoscopy
- Known or suspected bowel obstruction or severe gastrointestinal motility disorder
- Pregnancy or breastfeeding
- Participation considered inappropriate by the investigators for clinical or safety reasons
AI-Screening
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Trial Site Locations
Total: 1 location
1
San Pio Hospital
Benevento, Italy
Actively Recruiting
Research Team
G
Giuseppe Scaglione
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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