What this Trial Is About

Researchers are comparing three surgical methods—Endo-Surgi Plus endoscopic technique, Unilateral Biportal Endoscopic (UBE) technique, and microdiscectomy—for treating lumbar spinal stenosis, a condition where the spinal canal narrows and compresses nerves, leading to pain and mobility issues. This condition is common, especially in older adults, and surgery is often recommended when symptoms do not improve with conservative treatments. The study aims to evaluate the clinical effectiveness, complication rates, and surgical trauma differences among these three minimally invasive techniques. Patients in the study receive one of the three surgical treatments: Endo-Surgi Plus endoscopy, which uses a larger working channel for single-channel endoscopic surgery; UBE, which employs separate channels for viewing and working and allows use of traditional surgical tools; or microdiscectomy, a well-established minimally invasive surgery using a microscope. After surgery, all patients receive low-dose hormones, dehydrating agents, and neurotrophic drugs, and are advised to avoid heavy lifting and strenuous lumbar activities for three months. They also follow the same rehabilitation exercises and recovery education. The study includes a follow-up period of at least one year. Participants undergo outpatient visits, physical exams, and complete questionnaires during follow-up to assess recovery and outcomes. Researchers measure the Oswestry Disability Index scores one year after surgery to evaluate disability levels related to back pain. The study monitors for complications and surgical trauma differences. Outcome assessors and analysts remain blinded to treatment groups to reduce bias. The trial plans to include 324 patients, with statistical analyses comparing the effectiveness and safety of the three surgical approaches.

Comparision of Endoscopic Discectomy and Microdiscectomy for the Treatment of Lumbar Spinal Stenosis