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Comparison of an Acceleromyography- and Electromyography-based Neuromuscular Monitor With TOF-Watch 4 Monitor: a Pilot Study
Led by Huazhong University of Science and Technology · Updated on 2026-04-03
100
Participants Needed
2
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating a new device that combines electromyography (EMG) and acceleromyography (AMG) signals to monitor neuromuscular block during surgery. This study aims to compare the new technology with the TOF Watch4 SX, a widely used AMG-based neuromuscular monitor, to assess its accuracy in measuring neuromuscular block and posttetanic count. The new device's reliability has been recognized in rehabilitation but has not yet been tested for neuromuscular monitoring in surgery. The study involves observing patients undergoing elective surgery requiring muscle relaxation. The two monitored methods are the existing TOF Watch4 SX AMG device and the new DELSYS4 Wireless surface EMG technology, which captures both EMG and AMG signals wirelessly. Researchers will compare the train-of-four (TOF) and posttetanic count (PTC) measurements obtained from these devices during the perioperative period. Participants will be assessed during surgery with neuromuscular monitoring devices. Data collected include TOF and PTC correlations between the two devices and analysis of signal sources to improve monitoring. The study is observational, with no treatment changes, and aims to validate this new monitoring method. Participants will be adults aged 18 to 90 undergoing elective surgery with muscle relaxation, with safety and monitoring overseen throughout the procedure.
CONDITIONS
Brief Title
Comparison of an Acceleromyography- and Electromyography-based Neuromuscular Monitor With TOF-Watch ® Monitor
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 to 90 years
- American Society of Anesthesiologists Physical Status I to III
- Elective surgery requiring muscle relaxation
- Voluntary participation with signed informed consent
You will not qualify if you...
- Known neuromuscular disorder
- History of stroke
- Allergy to neuromuscular blocking agents
- Use of medications interfering with neuromuscular transmission
- Previous injury to the examined arm affecting nerve conduction
- Presence of a pacemaker
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - During surgery
Participants undergo monitoring using two neuromuscular devices during elective surgery requiring muscle relaxation.
1 perioperative visit (in-person)
Trial Site Locations
Total: 2 locations
1
Department of Anaesthesiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China, 430030
Actively Recruiting
2
Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China, 430030
Actively Recruiting
Research Team
H
Hua Zheng, Dr.
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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