Actively Recruiting
Comparison of an Acceleromyography- and Electromyography-based Neuromuscular Monitor With TOF-Watch ® Monitor
Led by Huazhong University of Science and Technology · Updated on 2026-04-03
100
Participants Needed
2
Research Sites
248 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A quantitative neuromuscular monitoring device is desirable to titrate the depth of neuromuscular block (NMB) during a procedure, and to prevent residual effects after removal of the endotracheal tube. Unfortunately, the most widely used monitoring technique acceleromyography (AMG) typically implies a series of cumbersome installation and calibration procedures that frequently precludes correct use of these devices in clinical practice. Electromyography (EMG) has recently attracted a lot of attention as an alternative strategy to compensate for the deficiency of AMG-based neuromuscular monitors. Nowadays, a new technology that allows for the simultaneous acquisition of EMG and AMG signals is commercially available. Although its reliability has been rapidly accepted in Physical Medicine and Rehabilitation, the use of the technique in neuromuscular monitoring has never been reported. The aim of the present study is to assess the validity of the new device for estimating the neuromuscular block by comparing with TOF Watch®-SX, which is the most widely accepted AMG-based neuromuscular monitor that has been practiced in the clinical arena for decades.
CONDITIONS
Official Title
Comparison of an Acceleromyography- and Electromyography-based Neuromuscular Monitor With TOF-Watch ® Monitor
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 to 90 years
- American Society of Anesthesiologists Physical Status I to III
- Elective surgery requiring muscle relaxation
- Voluntary participation with signed informed consent
You will not qualify if you...
- Known neuromuscular disorder
- History of stroke
- Allergic reaction to neuromuscular blocking agents
- Use of medications that interfere with neuromuscular transmission
- Previous injury to the examined arm affecting nerve conduction
- Presence of a pacemaker
AI-Screening
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Trial Site Locations
Total: 2 locations
1
Department of Anaesthesiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China, 430030
Actively Recruiting
2
Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China, 430030
Actively Recruiting
Research Team
H
Hua Zheng, Dr.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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