Actively Recruiting
Comparison of 5-ALA Photodynamic Therapy and CO2 Laser for Treating Persistent Low-Grade Cervical Lesions With High-Risk HPV Infection
Led by First Affiliated Hospital of Wenzhou Medical University · Updated on 2025-05-13
40
Participants Needed
1
Research Sites
94 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Non-RCT clinical trial comparing 5-ALA photodynamic therapy and CO2 laser for persistent high-risk HPV-related low-grade cervical lesions.
CONDITIONS
Official Title
Comparison of 5-ALA Photodynamic Therapy and CO2 Laser for Treating Persistent Low-Grade Cervical Lesions With High-Risk HPV Infection
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women aged 18 to 65 years with a history of sexual activity
- Confirmed persistent high-risk HPV positive infection for more than 1 year by HPV typing, mRNA, DNA, and cervical diagnostic tests
- Diagnosed with low-grade squamous intraepithelial lesions (LSIL) by cervical biopsy under colposcopy with more than 1 year interval
- No serious diseases affecting important organs
- Willing to receive treatment and follow-up and provide informed consent
- No use of HPV-related drugs in the past 3 months
You will not qualify if you...
- Persistent high-risk HPV infection
- History of total hysterectomy
- Presence of endometrial cancer, ovarian cancer, or other reproductive tract tumors
- Abnormal heart, liver, or kidney function, immune dysfunction, or immune diseases such as systemic lupus erythematosus
- Use of immunosuppressants, antiviral drugs, or glucocorticoids
- Pregnant or breastfeeding women
- Acute reproductive tract infection
- Uncontrolled diabetes
- Failure to receive full treatment and follow-up
- Refusal or inability to sign informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
first affiliated hospital of Wenzhou medical university
Wenzhou, Zhejiang, China, 325015
Actively Recruiting
Research Team
Y
YAN HU, PHD
CONTACT
K
kowthar mohamed shaie, master
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here