Actively Recruiting
Comparison of Anaesthesia Requirement for Ventilation With Endotracheal Tube Versus Proseal Laryngeal Mask Airway
Led by Sir Ganga Ram Hospital · Updated on 2026-04-27
160
Participants Needed
1
Research Sites
404 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Endotracheal tube (ETT) is the gold standard conduit for providing controlled ventilation during general anaesthesia (GA). however, the supra-glottic airway (SGA) devices in particular the laryngeal mask airway (LMA) and its variants have become a reliable alternative to ETT for carrying out controlled ventilation. Of the several variants of LMA available today, the proseal LMA (PLMA) is preferred for controlled ventilation. The various advantages of LMA includes, a lower incidence of postoperative sore throat and superior haemodynamic profile during surgery. However, one aspect of providing anaesthesia with LMA compared to ETT is the ability of LMA to maintain equivalent depth of anaesthesia with lower anaesthetic requirement, is quiet intriguing and evidence to this regard is very limited. By measuring the anaesthesia requirement using a robust computerised delivery system such as the closed loop anaesthesia delivery system (CLADS) we can establish for sure the anaesthesia required for maintaining intraoperative mechanical ventilation with the use of these two (ETT and PLMA) airway management devices. This randomised controlled study aims to calculate the anaesthesia requirement as determined by the total amount of propofol consumed for maintaining anaesthesia with ETT versus PLMA
CONDITIONS
Official Title
Comparison of Anaesthesia Requirement for Ventilation With Endotracheal Tube Versus Proseal Laryngeal Mask Airway
Who Can Participate
Eligibility Criteria
You may qualify if you...
- ASA physical status I or II
- Scheduled for elective laparoscopic cholecystectomy
- Age between 18 and 65 years
You will not qualify if you...
- Anticipated difficult airway
- Body mass index greater than 30 kg/m2
- Uncompensated cardiovascular disease such as uncontrolled hypertension, atrio-ventricular block, sinus bradycardia, congenital heart disease, reduced left ventricular compliance, or diastolic dysfunction
- Hepato-renal insufficiency
- Uncontrolled endocrine diseases like diabetes mellitus or hypothyroidism
- Known allergy or hypersensitivity to propofol
- History of drug dependence, substance abuse, or psychiatric illness
- Need for postoperative ventilation
- Refusal to provide informed consent
AI-Screening
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Trial Site Locations
Total: 1 location
1
Sir Ganga Ram Hospital
New Delhi, National Capital Territory of Delhi, India, 110060
Actively Recruiting
Research Team
N
Nitin Sethi, DNB
CONTACT
A
Amitabh Dutta, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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