Actively Recruiting
Comparison of Analgesic Efficacy and Opioid Consumption of Erector Spinae Plane Block Versus Serratus Anterior Block With Additional Pecto-Intercostal II Block in Breast-Conserving Surgery
Led by Kayseri City Hospital · Updated on 2026-04-21
70
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the effects of two different nerve block techniques, Erector Spinae Plane Block (ESPB) and a combination of Serratus Anterior Plane Block with Pectoral Nerve Block Type II (SAPB + PECS II), on pain management during and after breast cancer surgery. This randomized study involves 70 female patients aged 18 to 75 years with ASA physical status I-III. The goal is to compare how each technique influences the need for opioids and pain levels post-surgery. Before general anesthesia, patients will receive either the ESPB or the combined SAPB + PECS II block performed by the same anesthesiologist using ultrasound guidance. The ESPB targets the erector spinae muscle area with 35 mL of 0.25% bupivacaine, while the SAPB + PECS II technique uses a single needle entry to inject 15 mL and 20 mL of 0.25% bupivacaine into two specific muscle planes. All patients will undergo surgery under general anesthesia and receive morphine patient-controlled analgesia after surgery. Participants will be monitored continuously with standard anesthesia measures during surgery. Postoperative pain will be assessed using the Numerical Rating Scale for 24 hours or until discharge, alongside evaluation of nausea and vomiting. The total opioid consumption will be tracked via patient-controlled morphine analgesia. Data on pain scores and opioid use will be analyzed to understand the effectiveness of each nerve block method.
CONDITIONS
Brief Title
Comparison of the Analgesic Efficacy of Erector Spinae Plane Block in Breast-Conserving Surgery Versus Serratus Anterior Block Combined With Additional Pecto-Intercostal II Block
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 75 years
- Female patients
- ASA physical status I-III
- No history of bleeding or coagulation disorders
- Absence of neuropathy
- Preoperative breast region pain score less than 4 on the Numerical Rating Scale
You will not qualify if you...
- Presence of systemic or regional infection
- Known allergy to local anesthetics
- Unwillingness to participate in the study
AI-Screening
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Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of surgery
Participants receive either the Erector Spinae Plane Block or the Serratus Anterior Block combined with Pecto-Intercostal II Block before breast-conserving surgery under general anesthesia. The effectiveness of the nerve blocks is assessed using the pinprick test before surgery begins.
1 visit (in-person, surgery day)
Duration - Up to 24 hours or until discharge
Participants are monitored in the post-anesthesia care unit for 30 minutes and use a morphine patient-controlled analgesia (PCA) device to manage pain. Pain levels and nausea are assessed for up to 24 hours or until discharge.
Approximately 1 post-operative visit
Trial Site Locations
Total: 1 location
1
Kasyeri City Hospital
Kayseri, Kocasinan, Turkey (Türkiye), 38080
Actively Recruiting
Research Team
E
Erdoğan Rahmi Çinçin, Resident Doctor
Ç
Çiğdem Ünal Kantekin, Associate Professor of Medicin
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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