Actively Recruiting
Comparison Between Bipolar Transurethral Resection of the Prostate and Moses Assisted Holmium Laser Enucleation of the Prostate
Led by Fundacio Puigvert · Updated on 2026-04-29
130
Participants Needed
6
Research Sites
291 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Introduction: Multiple studies have demonstrated the superiority of HoLEP in aspects such as transfusión rates or postoperative stay. On the other hand, no differences have been observed in terms of functional outcomes between both techniques, and surgical times reported in different studies tend to be longer for HoLEP. These results likely contribute to TURP, especially with bipolar energy (Bi-TURP), continuing to be considered by many the gold standard for surgical treatment of BPH. Sofware and hardware upgrades to the Lumenis Pulse 120H. system in 2017, delivered MOSES 2.0, a single-use laser fibre used to perform MOSES augmented HoLEP (MoLEP). MoLEP has shown to be superior in intraoperative outcomes when compared to traditional HoLEP. The availability of new morcellators might also decrease surgical time for HoLEP. This changing landscape for BPH endoscopic surgery deserves a re-evaluation of the differences between Bi-TURP and MoLEP. Primary Objective: To compare the hospital stay of patients of patients undergoing MoLEP with those undergoing Bi-TURP. Secondary objectives: * To compare the surgical time of MoLEP with that of Bi-TURP. * To compare the bladder catheterization time aCer MoLEP with that of Bi-TURP. * To compare the postoperative complication rate patients undergoing MoLEP with those undergoing Bi-TURP. * To compare functional results of patients undergoing MoLEP with those undergoing Bi-TURP. This study is a prospective multicentric randomized and controlled trial. The study compares two types of BPH surgery without changing standard medical practice. The study will include patients who are candidates according to standard medical practice for BPH surgery. Patients will be randomized to one of two groups of treatment. * The MoLEP group will receive surgical treatment with MoLEP. * The Bi-TURP group will receive surgical treatment with Bi-TURP. Surgical technique and postoperative care will follow standard clinical practice at each participating centre.
CONDITIONS
Official Title
Comparison Between Bipolar Transurethral Resection of the Prostate and Moses Assisted Holmium Laser Enucleation of the Prostate
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with maximum flow rate < 15 ml/sec before surgery or with flow rate > 15 ml/sec and urodynamic study showing high-flow obstruction (bladder outlet obstruction index > 40)
- Patients with moderate to severe lower urinary tract symptoms (IPSS score between 8 and 35)
- Patients with prostate volume between 40 and 80 cc measured by ultrasound or MRI
You will not qualify if you...
- History of prior prostatic obstructive or urethral surgery
- Diagnosis of prostate neoplasia
- Diagnosis of urothelial neoplasia
- Lack of flowmetry or IPSS data before surgery
- Diagnosis or suspicion of hypo/acontractile detrusor before surgery
- Diagnosis or suspicion of neurogenic bladder or neurological disease
- History of pelvic radiation therapy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 6 locations
1
Complejo Hospitalario Universitario de Santiago de Compostela
Santiago de Compostela, A Coruña, Spain, 15706
Actively Recruiting
2
Fundacio Puigvert
Barcelona, BARCELONA, Spain, 08025
Actively Recruiting
3
Hospital Univesitari de Bellvitge
L'Hospitalet de Llobregat, BARCELONA, Spain, 08907
Not Yet Recruiting
4
Hospital Universitario Marqués de Valdecillas
Santander, Cantabria, Spain, 39008
Actively Recruiting
5
Hospital Universitario de Cabueñes
Gijón, Principality of Asturias, Spain, 33394
Actively Recruiting
6
Hospital Universitario Río Hortega
Valladolid, Valladolid, Spain, 47012
Actively Recruiting
Research Team
I
Ivan Schwartzmann Jochamowitz, MD
CONTACT
S
Silvia Mateu, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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