Actively Recruiting

Phase 4
Age: 18Years +
All Genders
NCT04588077

Comparison Between 2-dose Versus 3-dose Regimens of Heplisav B in Cirrhosis

Led by Mercy Medical Center · Updated on 2024-11-19

200

Participants Needed

1

Research Sites

428 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Investigators want to compare the seroconversion rates between two-dose and three-dose regimens of the hepatitis B vaccine (Heplisav B) among patients with cirrhosis, a randomized prospective study.

CONDITIONS

Official Title

Comparison Between 2-dose Versus 3-dose Regimens of Heplisav B in Cirrhosis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Cirrhosis patients aged 18 years or older attending the hepatology clinic at Mercy Medical Center between 09/2020 and 07/2021
  • Patients without immunity against Hepatitis B, defined as anti-HBs titer less than 10 mIU/ml
Not Eligible

You will not qualify if you...

  • History of serious allergic reaction to any hepatitis B vaccine, its components, or yeast
  • Previous exposure to hepatitis B virus
  • Patients who have undergone liver transplant
  • Under 18 years of age

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Mercy Medical Center

Baltimore, Maryland, United States, 21202

Actively Recruiting

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Research Team

C

CHAU TO, MD

CONTACT

P

Paul Thuluvath, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

4

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