Comparing Residential and Outpatient Weight Loss Programs for Children and Teens with Non-alcoholic Fatty Liver Disease

What this Trial Is About

Non-alcoholic fatty liver disease NAFLD is the most common chronic liver disease worldwide and has increased notably in children and adolescents due to rising obesity rates. This research aims to compare the effects of two different weight loss programs on liver health in young people with NAFLD. The study follows two groups to understand how residential and ambulatory lifestyle treatments impact liver steatosis and fibrosis in pediatric patients. Participants receive lifestyle management focused on increasing physical activity, improving diet, adopting healthy eating habits, and psychological support. One group undergoes residential treatment for up to one year, while the other participates in an ambulatory program with similar multidisciplinary care. Both approaches follow standard care procedures designed to address severe obesity and its effects on liver health. During the study, children and adolescents will be monitored for changes in liver fibrosis and steatosis after 6 and 12 months of lifestyle intervention. Researchers will assess liver health improvements using non-invasive measures, including Fibroscan tests and blood work such as ALT levels. The study aims to gather detailed information on how these weight loss programs affect liver disease progression over time.

Comparison Between the Efficacy of Residential and Ambulatory Weight Loss Programs for Pediatric Non-alcoholic Fatty Liver Disease