+1 877 705 1914• 24 / 7
HIPAA Compliant
ISO 27001 Certified

Actively Recruiting

Phase 3
Age: 21Years - 65Years
FEMALE
ID06947330

Comparing Ultrasound-Guided Erector Spinae Plane Block and Serratus Anterior Plane Block for Pain Relief After Modified Radical Mastectomy in Adult Women

Led by Kholoud Usama · Updated on 2025-04-27

100

Participants Needed

1

Research Sites

N/A

Total Duration

AI-Summary

What this Trial Is About

This research aims to compare two types of ultrasound-guided nerve blocks, the Erector Spinae Plane Block ESPB and the Serratus Anterior Plane Block SAPB, in adult women undergoing Modified Radical Mastectomy for breast cancer. The study evaluates which block provides better pain relief and which is safer regarding risks like pneumothorax and hemodynamic changes. Both methods are being assessed to improve postoperative pain management after breast surgery. Participants will be randomly assigned to receive either the ESPB or SAPB block after anesthesia but before surgical incision. Each block involves injecting a combination of bupivacaine and dexmedetomidine guided by ultrasound to target specific nerve areas. Lung ultrasound will be performed before and after surgery to check for pneumothorax. Those who develop pneumothorax will be excluded and treated accordingly. The study includes a 24-hour follow-up period to monitor pain levels and additional pain medication use. During the study, participants will have their pain measured at multiple time points up to 24 hours after surgery using the Visual Analog Score VAS. Researchers will also track total pain medication doses, duration of analgesia, vital signs, and the occurrence of pneumothorax. The study uses a double-blind design to ensure unbiased results. Overall participation spans the surgery day and the first postoperative day for close monitoring and data collection.

CONDITIONS

Brief Title

Comparison Between Erector Spinae Plane Block Versus Serratus Anterior Plane Block Regarding Analgesia Post Modified Radical Mastectomy

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here