Actively Recruiting

Phase Not Applicable
Age: 21Years - 85Years
All Genders
Healthy Volunteers
NCT06759116

Comparison Between Fentanyl and Dexmedetomidine As Adjuvant to Bupivacaine in Combined IPACK and Adductor Canal Block for Postoperative Analgesia After Knee Surgeries

Led by Zagazig University · Updated on 2025-01-14

111

Participants Needed

1

Research Sites

30 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study will be undertaken to compare the analgesic effects of of fentanyl versus dexmedetomidine as adjuvant to bupivacaine in combined IPACK and ACB for pain management after total knee arthroplasty.

CONDITIONS

Official Title

Comparison Between Fentanyl and Dexmedetomidine As Adjuvant to Bupivacaine in Combined IPACK and Adductor Canal Block for Postoperative Analgesia After Knee Surgeries

Who Can Participate

Age: 21Years - 85Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient acceptance
  • Cooperative patients
  • Age between 21 and 85 years old
  • Both males and females
  • Physical status ASA I, II, or III
  • Body Mass Index (BMI) of 35 kg/m2 or less
  • Undergoing elective unilateral knee surgeries (total knee arthroplasty, ACL reconstruction, or knee arthroscopy)
Not Eligible

You will not qualify if you...

  • Any contraindications to regional blocks such as coagulopathy or local infection at the injection site
  • Known allergy to bupivacaine, dexmedetomidine, or fentanyl
  • Advanced liver, kidney, heart, neurological, or respiratory diseases
  • Chronic opioid use exceeding 3 months or daily oral morphine use above 5 mg for 1 month

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

faculty of human medicine, Zagazig university hospitals

El Sharkia, Egypt

Actively Recruiting

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Research Team

D

Dina Sadek Salem, MD

CONTACT

S

Sherif Mowafy, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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