Actively Recruiting
Comparison Between Liquid Fibrin and Soft Laser Effects on Healing and Relapse After Lip Repositioning Surgery
Led by Damascus University · Updated on 2026-04-29
22
Participants Needed
1
Research Sites
40 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A gummy smile can negatively affect a patient's self-confidence and satisfaction with their appearance, leading many individuals to seek effective esthetic solutions. The etiology of this condition varies and may include vertical maxillary excess, short upper lip, hyperactive upper lip, gingival enlargement, or altered passive eruption. Lip Repositioning Surgery is one of the minimally invasive esthetic surgical procedures used to reduce the amount of gingival display during smiling. Despite its effectiveness, this surgery may be associated with challenges such as pain, swelling, delayed wound healing, and the possibility of postoperative relapse over time, which could compromise both esthetic and functional outcomes. To overcome these challenges and enhance surgical outcomes, adjunctive techniques have been introduced to promote healing and determine whether enhancing the biological healing process can reduce the rate of relapse after LRS. Among the most prominent of these are Injectable Platelet-Rich Fibrin (i-PRF) and Low-Level Laser Therapy (LLLT).
CONDITIONS
Official Title
Comparison Between Liquid Fibrin and Soft Laser Effects on Healing and Relapse After Lip Repositioning Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients of both genders
- Patients with a gummy smile in the upper front teeth region showing more than 3 mm due to upper lip hypermobility
- Age between 18 and 50 years
- Systemically healthy individuals classified as ASA physical status I or II
- Good oral hygiene with O'Leary Plaque Index 40% or less
- No previous lip repositioning surgery
You will not qualify if you...
- Pregnant or breastfeeding women
- History of facial Botox or filler injections
- Systemic diseases preventing use of local anesthesia
- Physical conditions impairing proper oral hygiene
- Smokers or alcohol consumers
- Inability or unwillingness to cooperate
- Inadequate width of attached gingiva
- Moderate to severe vertical maxillary excess needing jaw surgery
- Short upper lip
- Gingival display mainly caused by altered passive eruption requiring crown lengthening
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Faculty of Dentistry, Damascus university , Syria.
Damascus, Rif-dimashq Governorate, Syria
Actively Recruiting
Research Team
T
Tarek Qasem, DDS MSc PhD
CONTACT
W
Walaa albarry, DDS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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