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ID07532161

Study Comparing Liquid Platelet-Rich Fibrin and Low-Level Laser Therapy to Improve Healing and Reduce Relapse After Lip Repositioning Surgery for Gummy Smile

Led by Damascus University · Updated on 2026-04-29

22

Participants Needed

1

Research Sites

N/A

Total Duration

AI-Summary

What this Trial Is About

This research aims to compare the effects of Liquid Platelet-Rich Fibrin and Low-Level Laser Therapy on healing and relapse after lip repositioning surgery, a treatment for gummy smile caused mainly by upper lip hypermobility. The study addresses challenges such as pain, swelling, delayed healing, and relapse that can affect esthetic and functional outcomes. It explores whether these adjunctive techniques can improve healing and reduce relapse rates after surgery. Participants will be randomly assigned to one of two groups. One group will receive lip repositioning surgery followed by immediate injection of Liquid Platelet-Rich Fibrin along the incision margins. The other group will undergo the same surgery followed by application of low-level laser therapy immediately after surgery and on days 3, 7, 10, and 14 postoperatively. Both groups have similar surgical procedures but differ in the postoperative healing enhancement method. Participants will be monitored for gingival display at baseline and at 1, 3, and 6 months after surgery. Wound healing will be assessed weekly for 4 weeks. Other evaluations include postoperative pain, swelling, esthetic satisfaction, upper lip external and internal length, and any complications during and after surgery. The total involvement lasts at least 6 months with regular follow-ups to measure healing progress and relapse.

CONDITIONS

Brief Title

Comparison Between Liquid Fibrin and Soft Laser Effects on Healing and Relapse After Lip Repositioning Surgery

Research Team

T

Tarek Qasem, DDS MSc PhD

W

Walaa albarry, DDS

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