Day-case laparoscopic cholecystectomy in the management of gallbladder disease: a literature review.
Mohamed Abuahmed, Rahel Rashid
https://pubmed.ncbi.nlm.nih.gov/39340655Actively Recruiting
Phase Not Applicable
Age: 20Years - 60Years
All Genders
ID07131527
Comparative Study of Preoperative Oral Gabapentin Versus Diclofenac Sodium for Postoperative Pain Relief in Adults Undergoing Laparoscopic Cholecystectomy
Led by Sohag University · Updated on 2025-08-20
60
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are comparing the effects of two oral medications, Gabapentin and Diclofenac sodium, given before surgery to control pain after laparoscopic cholecystectomy in adults. The goal is to see which medicine provides better postoperative pain relief. The study is sponsored by Sohag University and involves adult patients diagnosed with chronic cholecystitis. Participants are randomly assigned to one of two groups: one group receives 600 mg of oral Gabapentin two hours before surgery, and the other group receives 100 mg of oral Diclofenac sodium two hours before surgery. Both treatments are given before the operation to compare their effects on pain after surgery. During the study, researchers will monitor pain levels eight hours after the operation to evaluate the effectiveness of each medication. Participants will be observed throughout the perioperative period, and their responses to the treatments will be assessed. The study includes adults aged 20 to 60 years and aims to provide clear information about pain management after laparoscopic gallbladder removal.
CONDITIONS
Brief Title
Comparison Between Oral Gabapentin Versus Diclofenac Sodium in Post-operative Analgesia Laparoscopic Cholecystectomy
Who Can Participate
Age: 20Years - 60Years
All Genders
Eligibility Criteria
You may qualify if you...
- Age from 20 to 60 years old
- Both sexes
- American Society of Anesthesiologists (ASA) physical status I or II
- Patients scheduled for laparoscopic cholecystectomy
You will not qualify if you...
- Patients with hypertension
- Pregnant women
- Obese patients with BMI greater than 35 kg/m2
- Alcoholics
- Patients with diabetes mellitus
- Patients who refuse to participate
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Treatment
Duration - Single day (perioperative period)
Participants receive a single dose of either oral Gabapentin or Diclofenac Sodium 2 hours before laparoscopic cholecystectomy surgery as postoperative analgesia.
1 perioperative visit
Post-operative Follow-up
Duration - 8 hours after operation
Participants are monitored for postoperative pain relief effects up to 8 hours after surgery.
1 follow-up visit within 8 hours post-surgery
Trial Site Locations
Total: 1 location
1
Sohag university hospital
Sohag, Egypt
Actively Recruiting
Loading map...
Research Team
M
Manar Z Ismaiel, Resident
A
Ahmed E Abdel Rahman, Professor
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Published Research Related To This Trial
Pharmacological and clinical implications of local anaesthetic mixtures: a narrative review.
C C Nestor, C Ng, P Sepulveda...
https://pubmed.ncbi.nlm.nih.gov/34904711Non-steroidal Anti-inflammatory Drugs: Clinical Implications, Renal Impairment Risks, and AKI.
John M LaForge, Kelsey Urso, Juan Martin Day...
https://pubmed.ncbi.nlm.nih.gov/36947330