Actively Recruiting
Comparison Between Transarterial Musculoskeletal Embolization and Platelet-Rich Plasma Injection for the Treatment of Greater Trochanteric Pain Syndrome
Led by Unidade Local de Saúde do Alto Ave, EPE · Updated on 2026-02-09
30
Participants Needed
1
Research Sites
103 weeks
Total Duration
On this page
Sponsors
U
Unidade Local de Saúde do Alto Ave, EPE
Lead Sponsor
S
Serviço de Ortopedia da ULS Alto Ave
Collaborating Sponsor
AI-Summary
What this Trial Is About
Greater Trochanteric Pain Syndrome (GTPS) is a common cause of lateral hip pain that can significantly affect daily activities and quality of life. Standard treatments include physical therapy, anti-inflammatory medications, and local injections, but many patients continue to experience persistent symptoms. This randomized controlled trial aims to compare two minimally invasive treatment options for GTPS: transarterial musculoskeletal embolization (TAME) and platelet-rich plasma (PRP) injection. Participants will be randomly assigned to receive either TAME or PRP. The main goal of the study is to evaluate which treatment is more effective in reducing pain. Secondary goals include comparing functional improvement, quality of life, and safety between the two treatments. Pain and functional outcomes will be assessed at baseline and during follow-up at 1, 3, 6, and 12 months after treatment. This study seeks to provide evidence on the effectiveness and safety of TAME compared with PRP injection for patients with Greater Trochanteric Pain Syndrome.
CONDITIONS
Official Title
Comparison Between Transarterial Musculoskeletal Embolization and Platelet-Rich Plasma Injection for the Treatment of Greater Trochanteric Pain Syndrome
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of GTPS confirmed by clinical and imaging assessments
- Persistent symptoms despite at least 3 months of conservative treatment (e.g., physical therapy, NSAIDs)
- Willingness to participate and provide informed consent
- Availability for follow-up assessments at 1, 3, 6, and 12 months post-treatment
You will not qualify if you...
- Prior hip surgery or other interventions (e.g., joint replacement, prior PRP injections or embolization)
- Severe osteoarthritis (Tonnis III)
- Active lumbar radiculopathy with pain, numbness, or weakness in a dermatomal distribution
- Contraindications for PRP injections (e.g., active infection, coagulopathy, antiplatelet or anticoagulation therapy)
- Pregnancy or breastfeeding
- Severe comorbidities that would interfere with participation
- Active cancer or other malignancies
AI-Screening
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Trial Site Locations
Total: 1 location
1
Unidade Local de Saúde do Alto Ave
Guimarães, Portugal
Actively Recruiting
Research Team
P
Pedro M M Lopes, MD
CONTACT
J
José F V Cavalheiro, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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