Actively Recruiting
Comparison Between Tranversus Abdominis Plane (TAP) Block With Only Bupivacaine and TAP Block With Bupivacaine Plus Ketamine in Reducing Postoperative Pain After Total Abdominal Hystrectomy
Led by Liaquat National Hospital & Medical College · Updated on 2026-03-25
30
Participants Needed
1
Research Sites
21 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this study is to know how effectively TAP block can reduce postoperative pain in total abdominal hystrectomy patients when given ketamine in addition to bupivacaine in TAP block and to compare it with the conventional TAP block with bupivacaine only. The main question it aims to answer is: Does intervention with ketamine in TAP block lowers the postoperative pain measured via visual analog scale and decreases the need for rescue analgesia? Patients will be assessed for pain in PACU( post anesthesia care unit), 6 hours, 12 hours and 24 hours postoperatively. Time of rescue analgesia will also be noted if given.
CONDITIONS
Official Title
Comparison Between Tranversus Abdominis Plane (TAP) Block With Only Bupivacaine and TAP Block With Bupivacaine Plus Ketamine in Reducing Postoperative Pain After Total Abdominal Hystrectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged between 25 to 60 years
- ASA grade I & II
- Undergoing total abdominal hysterectomy
You will not qualify if you...
- Body mass index over 35 kg/m2
- Patient refusal to participate
- Coagulation disorders
- History of allergy or hypersensitivity to local anesthetics
- Infection at the injection site
- Alcohol or drug abuse
- Cognitive or mental disorders
AI-Screening
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Trial Site Locations
Total: 1 location
1
gynae operation theatre at Liaquat National Hospital
Karachi, Sindh, Pakistan, 74800
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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