Actively Recruiting
Comparison Between Two Instrumentation Techniques on Postoperative Pain and Level of Neuropeptides
Led by Alexandria University · Updated on 2026-01-21
34
Participants Needed
1
Research Sites
25 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
General aim: assessment of post operative pain and time of preparation with the execution of manual-less technique and conventional technique. Specific aim: correlation between post operative pain and release of Substance P and Calcitonin gene-related peptide.
CONDITIONS
Official Title
Comparison Between Two Instrumentation Techniques on Postoperative Pain and Level of Neuropeptides
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with symptomatic irreversible pulpitis and apical periodontitis in mandibular molars with closed apex
- Healthy males and females (American Society of Anesthesiologists class I)
- Age between 18 and 50 years old
- Able to understand and use the numeric rating scale for pain
- Radiographs show no root resorption or abnormal anatomy
- Good oral hygiene and no periodontal disease
You will not qualify if you...
- Allergy to anesthetics
- Pregnancy
- Unrestorable teeth
- Currently taking analgesics
- Presence of root resorption or abnormal anatomy
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Alexandria Faculty of Dentistry
Alexandria, Egypt
Actively Recruiting
Research Team
H
hamdy Abou Almakarem, Msc
CONTACT
S
Sybel Moussa, PHD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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