Actively Recruiting

Phase Not Applicable
Age: 50Years +
MALE
NCT07416227

Comparison Between Water Vapor Thermal Therapy and Prostatic Artery Embolization in Treatment of Benign Prostatic Hyperplasia

Led by Ain Shams University · Updated on 2026-02-18

30

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this study is to compare the effectiveness of Rezum therapy versus Prostatic Artery Embolization in managing moderate-to-severe lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH), with the primary endpoint being the improvement in the International Prostate Symptom Score (IPSS) over a 6-month follow-up period. Secondary endpoints include changes in post-void residual urine (PVR), maximum urinary flow rate (Qmax), patient-reported quality of life (QoL), and the preservation of ejaculatory and overall sexual function as assessed by validated questionnaires. This study aims to provide evidence-based guidance for optimizing treatment strategies for men with BPH, particularly those seeking alternatives to pharmacological therapy.

CONDITIONS

Official Title

Comparison Between Water Vapor Thermal Therapy and Prostatic Artery Embolization in Treatment of Benign Prostatic Hyperplasia

Who Can Participate

Age: 50Years +
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Age ≥50 years.
  • IPSS ≥13.
  • Prostate volume between 30-80 mL.
  • Maximum urinary flow rate (Qmax) ≤15 mL/sec in patients with voiding LUTs.
  • Patients not responding to medical treatment.
Not Eligible

You will not qualify if you...

  • History or suspicion of prostate cancer.
  • Previous prostate surgery or minimally invasive BPH intervention.
  • Neurological bladder dysfunction.
  • Active urinary tract infection.

AI-Screening

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Trial Site Locations

Total: 1 location

1

Ain Shams University

Cairo, Abbassia, Egypt, 00202

Actively Recruiting

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Research Team

S

Seif AbdElmomen Yosef, MBBCh, MSc Faculty of Medicine

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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