Study of Bone Mineral Density Differences in Women With Singleton and Twin Pregnancies in the Third Trimester Using Questionnaires and REMS Ultrasound Technology

What this Trial Is About

Researchers are evaluating bone mineral density BMD and fracture risk in women with singleton and twin pregnancies during the third trimester. The study aims to identify differences in BMD between these groups and assess the relationship between BMD and maternal factors like age, body mass index BMI, and medical history. It also investigates how BMD correlates with scores from specific questionnaires related to fracture risk and bone health quality of life. Women between 35 and 41 weeks of pregnancy will complete two questionnaires developed by the Fragility Fracture Observatory OFF that assess fracture risk, dietary calcium intake, and adherence to the Mediterranean diet. Bone health will be evaluated using a radiation-free ultrasound densitometry technology called REMS, performed with the EchoStation device. This device measures bone density and fragility through a 40-second ultrasound scan of the femoral neck, providing results similar to a DEXA scan but without radiation exposure. Participants will provide their medical, obstetric, and dietary history and complete questionnaires during enrollment. Bone density and fragility will be monitored during the third trimester. Researchers will analyze BMD differences, maternal clinical parameters, and questionnaire results over about six weeks until delivery. The study includes detailed bone assessments, lifestyle evaluations, and maternal health monitoring to better understand bone health changes during pregnancy in both singleton and twin pregnancies.

Comparison of Bone Mineral Density in the Third Trimester Between Women in Singleton and Twin Pregnancies Using Questionnaires and REMS Densitometric Examination