Actively Recruiting

Age: 40Years +
All Genders
Healthy Volunteers
NCT06682832

Comparison of Clinical Status of Individuals With COPD and Preserved Ratio Impaired Spirometry

Led by Hacettepe University · Updated on 2026-03-31

54

Participants Needed

1

Research Sites

49 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Despite the globally varying high prevalence rate of the PRISm phenotype, there are no guidelines for its diagnostic evaluation and management. Further studies are needed on appropriate approaches for individuals with PRISm to improve respiratory symptoms and prognosis. As research continues to evolve, PRISm needs to be recognized as a critical component of pulmonary assessments and at-risk individuals need to be provided with appropriate treatment and follow-up to prevent progression to COPD. There are no studies in the literature comparing PRISm, respiratory muscle strength, peripheral muscle strength and oxygenation, arterial stiffness, physical activity level and sleep level in COPD and healthy individuals. The aim of this study was to compare respiratory muscle strength, peripheral muscle strength and oxygenation, arterial stiffness, physical activity level and sleep level in PRISm, COPD and healthy subjects.

CONDITIONS

Official Title

Comparison of Clinical Status of Individuals With COPD and Preserved Ratio Impaired Spirometry

Who Can Participate

Age: 40Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Being 40 years old or older
  • Diagnosed with PRISm (for PRISm group)
  • Diagnosed with COPD and clinically stable (for COPD group)
  • No known chronic health problems (for healthy individuals)
  • Willing to volunteer for the study
  • Able to cooperate with study measurements
Not Eligible

You will not qualify if you...

  • Diagnosed with COPD (for PRISm group exclusion)
  • Severe orthopedic, neurological, or cardiac diseases
  • Currently experiencing COPD exacerbation (for COPD group exclusion)
  • Known chronic disease (for healthy individuals exclusion)
  • Not willing to volunteer for the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hacettepe University

Ankara, Turkey (Türkiye), 06560

Actively Recruiting

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Research Team

E

Ece Kumlu, M.Sc

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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