Actively Recruiting
Comparison of Cloxacillin and Benzylpenicillin in Penicillin Susceptible S. Aureus Bacteraemia
Led by Region Skane · Updated on 2026-04-30
420
Participants Needed
1
Research Sites
172 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this study is to investigate if benzylpenicillin is a better treatment option than cloxacillin in patients with penicillin-susceptible Staphylococcus aureus bacteraemia.
CONDITIONS
Official Title
Comparison of Cloxacillin and Benzylpenicillin in Penicillin Susceptible S. Aureus Bacteraemia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 18 years or older with penicillin susceptible Staphylococcus aureus bacteraemia (PSSA)
- Able to provide written informed consent
You will not qualify if you...
- Allergy to penicillin
- Unable to give informed consent
- Concomitant growth of other clinically significant bacteria in blood cultures
- Neutropenia
- Prior antibiotic treatment for 96 hours or more
- Unable to use oral follow-up medication with flucloxacillin or penicillin V/amoxicillin (e.g., prosthetic joint infection)
- Patients in terminal palliation with expected death within 7 days
- Treating physician believes cloxacillin is not a first-line treatment
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Skånes universitetssjukhus, Region Skåne
Lund, Sweden, 22467
Actively Recruiting
Research Team
M
Malin Hagstrand Aldman, PhD
CONTACT
L
Lisa I Påhlman, PhD, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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