Actively Recruiting

Phase Not Applicable
Age: 18Years - 45Years
FEMALE
NCT07411521

Comparison of Combined Spinal Epidural Analgesia and Erector Spinae Plane Block After Elective Cesarean Section

Led by Bursa City Hospital · Updated on 2026-02-17

90

Participants Needed

1

Research Sites

21 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Postoperative pain after cesarean section can significantly affect maternal recovery, early mobilization, and patient satisfaction. Regional anesthesia techniques are widely used to improve postoperative analgesia and reduce opioid consumption. Combined spinal-epidural analgesia is commonly used for cesarean section and provides effective pain control but may be associated with technical difficulties and potential complications. The erector spinae plane block is a newer ultrasound-guided regional anesthesia technique that has shown promising results for postoperative pain management in various surgical procedures. The aim of this study is to compare the postoperative analgesic effectiveness of combined spinal-epidural analgesia and the erector spinae plane block in patients undergoing elective cesarean section. Pain intensity will be assessed using the visual analog scale at multiple postoperative time points. Maternal recovery will be evaluated using the Obstetric Quality of Recovery-11 questionnaire. Secondary outcomes will include postoperative nausea, pruritus, time to first analgesic request, mobilization time, and patient satisfaction. This study will help determine whether the erector spinae plane block can provide comparable or improved postoperative pain control with fewer complications compared to combined spinal-epidural analgesia.

CONDITIONS

Official Title

Comparison of Combined Spinal Epidural Analgesia and Erector Spinae Plane Block After Elective Cesarean Section

Who Can Participate

Age: 18Years - 45Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Female patients aged 18 to 45 years
  • Scheduled for elective cesarean section under regional anesthesia
  • American Society of Anesthesiologists (ASA) physical status I-II
  • Singleton pregnancy at term gestation
  • Ability to understand the study protocol and provide written informed consent
Not Eligible

You will not qualify if you...

  • Refusal to participate in the study
  • Contraindications to regional anesthesia such as coagulopathy, infection at injection site, or severe hypovolemia
  • Known allergy to local anesthetics or study medications
  • Body mass index (BMI) greater than 40 kg/m8
  • Chronic opioid use or chronic pain disorders
  • Neurological disorders affecting sensory assessment
  • Severe obstetric complications such as preeclampsia, placenta previa, or fetal distress

AI-Screening

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Trial Site Locations

Total: 1 location

1

Bursa City Hospital

Bursa, Nilüfer, Turkey (Türkiye), 16110

Actively Recruiting

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Research Team

Y

Yasemin Nur Tekin

CONTACT

E

Emre ULUSOY

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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