Real-World Study Comparing Conservative and Endovascular Treatments for Spontaneous Superior Mesenteric Artery Dissection

What this Trial Is About

Researchers are studying Spontaneous Isolated Superior Mesenteric Artery Dissection SISMAD, a condition increasingly diagnosed but with limited evidence guiding treatment. This observational study compares the effects of conservative treatment versus endovascular treatment to understand which approach better helps patients with this condition. The study is sponsored by Xiangya Hospital of Central South University and aims to provide real-world evidence to improve clinical decisions for SISMAD. Participants receive either endovascular treatments or conservative care. Conservative treatment includes managing blood pressure, bowel rest, antithrombotic therapy, nutritional support, and pain control. The study observes these treatment groups over time to assess outcomes without altering usual care. There is no randomization or blinding since this is an observational study. Participants will be followed for up to five years with regular monitoring of symptom relief and survival. Researchers will also track reintervention needs, recurrence, disease complications, and artery remodeling. Patients will undergo clinical evaluations and imaging to assess their conditions progress. The study involves long-term observation to gather comprehensive data on treatment effects and safety.

Comparison of Conservative and Endovascular Treatment for Spontaneously Isolated Superior Mesenteric Artery Dissection