Actively Recruiting
Comparison of Cryoablation of Pericapsular Nerve Group (PENG) to Fascia Iliaca Catheter in Patients With a Hip Fracture
Led by University of Minnesota · Updated on 2025-11-25
150
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating pain control methods after hip fracture surgery in adults aged 18 to 85. This Phase 4 trial compares cryoablation of the Pericapsular Nerve Group (PENG) with the use of a fascia iliaca catheter to determine which approach offers better pain relief 30 days after surgery. The study is sponsored by the University of Minnesota and focuses on improving recovery outcomes for patients with hip fractures. Participants will be randomly assigned to one of two treatment groups. One group will receive an ultrasound-guided PENG block with 20 mL of 0.5% bupivacaine followed by cryoablation of the PENG nerves. The other group will receive an ultrasound-guided fascia iliaca compartment catheter with an initial bolus of 20 mL of 0.5% bupivacaine and a continuous infusion of 0.2% ropivacaine at 10 mL per hour. Both interventions are delivered after hip fracture repair surgery. During the study, researchers will monitor participants' maximum pain scores 30 days after surgery, opioid use on days 0 through 7 post-surgery, functional pain scores during the first week, length of hospital stay, time to first walking, and the number of patients who have returned home by 30 days. The study involves close follow-up over the first month after surgery to assess pain control and recovery progress.
CONDITIONS
Brief Title
Comparison of Cryoablation of Pericapsular Nerve Group (PENG) to Fascia Iliaca Catheter in Patients With a Hip Fracture
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients undergoing hip fracture repair aged 18-85.
You will not qualify if you...
- Patients who have an exclusion to regional anesthesia.
- Patients who are pregnant assessed via self-report or pregnancy test if they have taken one.
- Non-English speakers
- Patients who already had their fracture repaired
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 7 days post surgery
Participants receive either a PENG block with cryoablation or a fascia iliaca compartment block with catheter for pain management after hip fracture surgery.
Daily visits for up to 7 days post surgery
Duration - Up to 30 days post surgery
Participants are monitored for pain scores, opioid use, functional recovery, length of hospital stay, time to first ambulation, and return home status up to 30 days after surgery.
1 visit at 30 days post surgery
Trial Site Locations
Total: 1 location
1
University of Minnesota
Minneapolis, Minnesota, United States, 55414
Actively Recruiting
Research Team
C
Candace Nelson
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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