Actively Recruiting
Comparison of Cumulative Opioid Consumption Between Variable-Rate Feedback Infusion and Fixed-Rate Basal Infusion Modes of Intravenous PCA Following Mixed Surgery
Led by Beijing Tiantan Hospital · Updated on 2026-05-14
1170
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
Sponsors
B
Beijing Tiantan Hospital
Lead Sponsor
S
Shenzhen University General Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Perioperative pain management affects patient recovery. However, the rate of moderate to severe postoperative pain is as high as 73.8%, which hinders recovery and increases the risk of complications. Although opioids are the first-line analgesics, excessive use leads to adverse reactions. The traditional fixed-rate PCA mode is difficult to match the changes in postoperative pain. This study will compare different PCA mode optimization strategies, assuming that they can reduce opioid dosage, improve analgesic effect, and reduce adverse reactions, providing high-quality evidence-based basis for postoperative analgesia and promoting individualized and intelligent management.
CONDITIONS
Official Title
Comparison of Cumulative Opioid Consumption Between Variable-Rate Feedback Infusion and Fixed-Rate Basal Infusion Modes of Intravenous PCA Following Mixed Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged between 18 to 65 years
- American Society of Anesthesiologists physical status I to III
- Scheduled for elective mixed surgery including thoracic, abdominal, spinal, orthopedic, or cranial procedures using minimally invasive or open approaches
You will not qualify if you...
- Allergy to patient-controlled analgesia medications
- Presence of chronic pain syndromes
- Presence of psychiatric disorders
- Severe cardiovascular, cerebrovascular, renal, or hepatic dysfunction
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Beijing Tiantan Hospital, Beijing, Beijing 100070
Beijing, China
Actively Recruiting
Research Team
F
Fang Luo
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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