Actively Recruiting
Comparison of Customized Allogenic Versus Autogenous Bone Block Graft for Alveolar Ridge Augmentation
Led by Medical University of Graz · Updated on 2026-02-18
26
Participants Needed
1
Research Sites
382 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this study is to determine whether jawbone augmentations using allogeneic and autogenous bone blocks lead to comparable three-dimensional clinical and radiological outcomes. In addition, the study seeks to investigate whether there are differences regarding safety, biocompatibility, complications, and PROMs. Furthermore, it aims to clarify whether differences exist between the two groups with respect to implant condition (one year after implantation and during annual follow-ups for up to five years).
CONDITIONS
Official Title
Comparison of Customized Allogenic Versus Autogenous Bone Block Graft for Alveolar Ridge Augmentation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Have 1 to 4 missing teeth that need replacement with dental implants
- Have jawbone ridge width less than 5 mm at the ideal implant site as measured by cone beam CT
- Be medically healthy with no known allergies to antibiotics
- Be a non-smoker, light smoker (less than 10 cigarettes per day), or a former smoker who quit at least 5 years ago
- Have good periodontal health confirmed by clinical exam with bleeding and plaque scores below 25% and at least one neighboring natural tooth
- Be 18 years of age or older
You will not qualify if you...
- Have any contraindications against implant or augmentation treatments such as advanced systemic diseases, corticosteroid medication, immunodeficiency, pregnancy, breastfeeding, or lack of safe contraception
- Have treatments or diseases affecting bone turnover, bone tissue, or metabolism such as bisphosphonate use, local radiotherapy, or skeletal immaturity
- Have pathological fractures from conditions like Paget's disease or metastatic bone disease
- Have any active cancer or are undergoing cancer treatment
- Have known allergies or hypersensitivity to the study drugs or investigational products
- Have persistent compartment syndrome or residual neurovascular problems from compartment syndrome
AI-Screening
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Trial Site Locations
Total: 1 location
1
Department of Dental Medicine and Oral Health, Division of Oral Surgery and Orthodontics, Medical University of Graz
Graz, Styria, Austria, 8010
Actively Recruiting
Research Team
M
Michael Payer, Assoz.Prof.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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