Actively Recruiting
Comparison of Diagnostic Performances of 3D FLAIR, DIR and PSIR Sequences in Optic Neuritis
Led by University Hospital, Strasbourg, France · Updated on 2024-07-10
60
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Ultimately improve the care of patients suffering from multiple sclerosis (1st cause of acquired non-traumatic disability in adults) and NMO spectrum diseases by using more efficient MRI sequences than the FLAIR sequence commonly used in detection of optic neuritis. In the literature, many studies have already focused on comparing the sensitivity of detection of white matter demyelination plaques using FLAIR, PSIR or DIR sequences. Some authors have shown better sensitivity of the PSIR sequence in the detection of demyelinating lesions of the marrow in multiple sclerosis compared to conventional sequences. Others have shown better performance of the combined use of PSIR and DIR sequences compared to the FLAIR sequence in the detection of cortical lesions in multiple sclerosis. However, in the context of optic neuritis, few comparative studies comparing these three sequences have been carried out: A 2022 study showed better diagnostic sensitivity of optic neuritis of the DIR sequence compared to the FLAIR sequence. A possible better diagnostic performance of a sequence not used in current practice in the detection of optic neuritis (PSIR and DIR sequences), would be possible to justify their use on a larger scale and ultimately improve patient care.
CONDITIONS
Official Title
Comparison of Diagnostic Performances of 3D FLAIR, DIR and PSIR Sequences in Optic Neuritis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years or older
- Diagnosed with multiple sclerosis or an NMO spectrum disease
- Have had an MRI including 3D FLAIR, 3D DIR, and 3D PSIR sequences
- Brain MRI performed between April 1, 2019 and November 30, 2021
- No opposition to reuse of medical data for scientific research
You will not qualify if you...
- Oppose reuse of medical data for scientific research
- MRI images have artifacts that prevent clear interpretation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Service de Radiologie II, CHU de Strasbourg
Strasbourg, Les Hôpitaux Universitaires de Strasbourg, France, 67091
Actively Recruiting
Research Team
F
François-Daniel ARDELLIER, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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