Actively Recruiting
A Comparison of Diagnostic Testing Modalities in the Assessment of Asthma
Led by Portsmouth Hospitals NHS Trust · Updated on 2025-07-17
2000
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Asthma is a common condition marked by breathing difficulties, coughing, and wheezing. Diagnosing asthma relies on identifying airflow obstruction, airway sensitivity, and inflammation, but international guidelines vary in their criteria. This research evaluates how well these guidelines agree in diagnosing asthma and explores additional lung function tests like impulse oscillometry (IOS), which is not commonly included in guidelines but available at the Portsmouth lung function service. The study involves analyzing routine lung function data from patients attending the severe asthma service at Queen Alexandra Hospital in Portsmouth. It compares standard diagnostic tests recommended by international guidelines with IOS, a simple, non-invasive test measuring lung function. The goal is to see if IOS can improve the accuracy and ease of diagnosing asthma in adults. Participants' lung function data will be reviewed using both guideline-based and additional criteria, focusing on how well each method identifies asthma. Outcomes include scores based on international asthma guidelines and numbers related to non-guideline lung function tests, assessed about four weeks after recruitment. The study uses an opt-out consent process and aims to provide insights that may enhance asthma diagnosis and management.
CONDITIONS
Brief Title
A Comparison of Diagnostic Testing Modalities in the Assessment of Asthma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 18 years or over
- Have attended full asthma workups from November 2021 to present
- Willing and able to consent to use of their data in this study
- Referred to the Portsmouth asthma service for diagnosis and management of presumed asthma
- Patients with co-existing conditions such as obesity, bronchiectasis, or COPD are eligible
You will not qualify if you...
- Unable to understand the study or provide informed consent (e.g., insufficient English without an interpreter)
- Have other primary respiratory conditions such as interstitial lung disease (ILD)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Ongoing during routine outpatient visits starting from November 2021
Participants undergo routine outpatient lung function tests including impulse oscillometry and other lung function indices to assess asthma diagnosis.
Visits aligned with routine outpatient lung function testing
Duration - Up to 4 weeks after recruitment
Participants' lung function data and asthma diagnostic outcomes are analyzed over time to compare different diagnostic approaches.
No additional visits required; data analysis based on collected lung function tests
Trial Site Locations
Total: 1 location
1
Portsmouth Hospitals University NHS Trust
Portsmouth, United Kingdom
Actively Recruiting
Research Team
C
celia Selvin-Premkumar
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here