Actively Recruiting
Comparison of Different Methods to Calculate Pendelluft by Electrical Impedance Tomography in Mechanically Ventilated Patients
Led by University of Sao Paulo General Hospital · Updated on 2024-07-10
15
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The Pendelluft phenomenon is an important cause of lung damage in spontaneously breathing mechanically ventilated patients since it considerably increases the stress on the lung parenchyma in the dependent areas. It can result in a local driving pressure up to three times higher than the global driving pressure. The measurement of Pendelluft is still uncertain in the literature, and although various methods have been proposed, not all have the same meaning in terms of pulmonary overstress and overstrain. This study proposes a comparative analysis of different ways to calculate and estimate the stress imposed on the lung parenchyma by Pendelluft in terms of regional volume and local driving pressure through electrical impedance tomography.
CONDITIONS
Official Title
Comparison of Different Methods to Calculate Pendelluft by Electrical Impedance Tomography in Mechanically Ventilated Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients under invasive mechanical ventilation intubated due to respiratory failure in pressure support mode (weaning phase)
You will not qualify if you...
- Age less than 18 years
- Sedation or neuromuscular blockade
- Absence of respiratory effort
- Contraindications to esophageal balloon catheter or electrical impedance tomography belt positioning
- Presence of pneumothorax or active air leaks
- Hemodynamic instability
- Absence of informed consent
AI-Screening
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Trial Site Locations
Total: 1 location
1
Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da USP
São Paulo, Brazil, 05403-900
Actively Recruiting
Research Team
M
Marcelo BP Amato, MD PhD
CONTACT
E
Emily Sofia Ceron
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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