Actively Recruiting
Comparison of Early Caffeine Administration Vs Supportive Therapy in Preventing Acute Kidney Injury
Led by Muhammad Aamir Latif · Updated on 2025-12-26
236
Participants Needed
1
Research Sites
25 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Recent observational data point towards a reduced incidence of acute kidney injury (AKI) with early caffeine use, but high-quality randomized controlled trials comparing early caffeine initiation to supportive therapy alone are lacking. This study aims to fill this critical gap by comparing the efficacy of early caffeine administration versus supportive therapy in preventing AKI in preterm neonates.
CONDITIONS
Official Title
Comparison of Early Caffeine Administration Vs Supportive Therapy in Preventing Acute Kidney Injury
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Neonates of any gender
- Neonates with gestational age <32 weeks
- Admitted within 6 hours of birth
You will not qualify if you...
- Major congenital anomalies
- Severe birth asphyxia (Apgar <3 at 10 min)
- Pre-existing renal anomalies
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
The Children's Hospital & The Institute of Child Health
Multan, Punjab Province, Pakistan, 66000
Actively Recruiting
Research Team
N
Nazia Fatima, FCPS
CONTACT
R
Rabia Saleem, FCPS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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