Actively Recruiting

Phase Not Applicable
Age: 40Years - 70Years
All Genders
NCT06903936

Comparison of the Effect of Genicular Nerve Block and Physical Therapy in Patients With Knee Osteoarthritis

Led by Ahi Evran University Education and Research Hospital · Updated on 2026-02-20

66

Participants Needed

2

Research Sites

25 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Knee arthritis is a chronic joint disease that causes pain, disability and impaired quality of life, leading to significant social and health problems worldwide. Moreover, these public and economic impacts related to osteoarthritis of the knee are expected to increase in the future. With the global increase in the proportion of the elderly population, overall obesity rates and the associated incidence of osteoarthritis of the knee, clinicians are now focusing on new treatment strategies. The diagnosis is usually made by history, physical examination and radiography (X-ray) and there is no need for additional examination. Today, both non-surgical and surgical interventions are used in the treatment of knee arthritis. Non-surgical options include patient education, weight loss, physical therapy (PT), support or foot orthosis, oral painkillers, non-cortisol anti-inflammatory drugs, cortisols, hyaluronic acid, plasma injections rich in platelets, prolotherapy, stem cell therapy and genicular nerve blocks. The aim of the study was to compare the benefits of genicular nerve block and physical therapy in volunteers with knee pain for more than 3 months like you and to determine the most appropriate method. In this study, Genicular nerve block and Physical therapy in patients with knee arthritis; * Effects on knee pain, mobility and functional ability * It is aimed to examine the effects on equilibrium parameters. A total of 66 participants will be included in the study. Participants will be randomly assigned to three groups by envelope selection method. Your treatment method will be determined according to the treatment method in the envelope you choose.

CONDITIONS

Official Title

Comparison of the Effect of Genicular Nerve Block and Physical Therapy in Patients With Knee Osteoarthritis

Who Can Participate

Age: 40Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Be between 40 and 70 years old
  • Have radiological knee osteoarthritis grade two or three by Kellgren-Lawrence classification
  • Have knee pain lasting at least three months
  • Agree to participate and provide informed consent
Not Eligible

You will not qualify if you...

  • Pregnancy
  • Malignancy
  • Epilepsy
  • History of cardiac pacemaker
  • Received glucocorticosteroid, hyaluronic acid, platelet-rich plasma, or genicular nerve block injections in the past six months
  • Received physical therapy in the last six months
  • Taken oral glucosamine in the last six months
  • Use of anticoagulants
  • History of systemic inflammatory disease
  • History of fracture or surgery in the lower extremity
  • Open wounds on the knees
  • History of systemic infection
  • Inability to cooperate
  • History of neuromuscular disease affecting balance
  • Unwillingness to participate in the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Kirsehir Ahi Evran University Physical Medicine and Rehabilitation Hospital

Kirşehi̇r, Kirşehi̇r, Turkey (Türkiye), 40100

Actively Recruiting

2

Ahi Evran University Hospital

Kırşehir, Kırşehir, Turkey (Türkiye), 40100

Actively Recruiting

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Research Team

H

Hacer I Altay Caglar, ra

CONTACT

N

Nazife Kapan, assoc prof

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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