Actively Recruiting
Comparison of the Effectiveness of Paracetamol With Ibuprofen or Paracetamol With Metamizole in Treating Pain in Acute Pancreatitis in Children
Led by Medical University of Warsaw · Updated on 2025-08-24
78
Participants Needed
1
Research Sites
91 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of the study is to assess the effectiveness and tolerance of pain treatment in AP in children using intravenous paracetamol in combination with ibuprofen or paracetamol in combination with metamizole. The study is prospective, interventional, and randomized.
CONDITIONS
Official Title
Comparison of the Effectiveness of Paracetamol With Ibuprofen or Paracetamol With Metamizole in Treating Pain in Acute Pancreatitis in Children
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of acute pancreatitis according to INSPPIRE criteria
- Age from 3 to 18 years
- Abdominal pain on admission with a score of 4 or higher on the Numerical Rating Scale (NRS) or FLACC
- No pain medication taken before enrollment or last dose of paracetamol, ibuprofen, or metamizole taken at least 6 hours before enrollment
- Consent from legal guardians and the child if 16 years or older to participate in the study
You will not qualify if you...
- Pain medication taken less than 6 hours before enrollment
- Allergy to acetylsalicylic acid, other NSAIDs, paracetamol, or metamizole
- Inflammatory bowel disease
- Active gastrointestinal bleeding
- Gastric or duodenal ulcer disease
- Chronic use of paracetamol, NSAIDs, or metamizole
- Liver failure
- Heart failure classified as NYHA II-IV
- Acute or chronic kidney failure
- Cancer
- Lack of consent from legal guardians or patient if older than 16 years
AI-Screening
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Trial Site Locations
Total: 1 location
1
Department of Paediatric Gastroenterology and Nutrition
Warsaw, Poland, 02-091
Actively Recruiting
Research Team
A
Aleksandra Banaszkiewicz, M.D., PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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