Actively Recruiting

Phase Not Applicable
Age: 65Years - 85Years
All Genders
NCT06731049

Comparison of the Effectiveness of Treadmill-Based Walking and Dual-Task Walking Training in Alzheimer's Disease

Led by Istanbul University - Cerrahpasa · Updated on 2026-03-31

46

Participants Needed

1

Research Sites

121 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Alzheimer's disease is a neurodegenerative condition that affects both cognitive and motor functions, making daily life activities more challenging. Motor functions, especially walking and balance, begin to deteriorate early in the disease and progress in parallel with cognitive decline. Dual-task performance, which refers to the ability to perform both motor and cognitive tasks simultaneously, significantly decreases in individuals with Alzheimer's disease. Current studies suggest that dual-task exercises can improve both cognitive and motor functions. In this context, treadmill-based dual-task training emerges as a promising approach to mitigate the effects of Alzheimer's disease. The study hypothesizes that treadmill-based dual-task training will have more positive effects on motor and cognitive parameters compared to treadmill exercise alone in individuals with Alzheimer's disease. The main research question of this study is whether treadmill-based dual-task exercise training, designed with progressively more challenging cognitive and motor tasks and tailored to the individual, results in significant improvements in motor and cognitive parameters, as well as daily living activities and dual-task performance, compared to a group that only undergoes treadmill exercise.

CONDITIONS

Official Title

Comparison of the Effectiveness of Treadmill-Based Walking and Dual-Task Walking Training in Alzheimer's Disease

Who Can Participate

Age: 65Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of Alzheimer's disease by a neurologist using NINCDS-ADRDA criteria
  • Early or middle stage Alzheimer's disease based on Clinical Dementia Rating Scale
  • Receiving treatment for Alzheimer's disease for at least 1 month
  • Able to walk at least 400 meters in 6-Minute Walk Test
  • Able to read and understand instructions in Turkish
Not Eligible

You will not qualify if you...

  • Diagnosis of Lewy body dementia, frontotemporal dementia, or other dementias
  • Participation in a structured exercise program within 6 months before the study
  • Presence of pulmonary, neurological, musculoskeletal, or rheumatological diseases hindering walking
  • Unstable medical conditions like uncontrolled diabetes or hypertension
  • Visual or hearing problems that impair communication
  • Behavioral issues that prevent participation in exercise

AI-Screening

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Trial Site Locations

Total: 1 location

1

İstanbul University-Cerrahpaşa

Istanbul, Turkey (Türkiye)

Actively Recruiting

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Research Team

K

Kübra Nur Menengiç, MSc

CONTACT

İ

İpek Yeldan, Prof. Dr.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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