Actively Recruiting
Comparison of the Effectiveness of Treadmill-Based Walking and Dual-Task Walking Training in Alzheimer's Disease
Led by Istanbul University - Cerrahpasa · Updated on 2026-03-31
46
Participants Needed
1
Research Sites
121 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Alzheimer's disease is a neurodegenerative condition that affects both cognitive and motor functions, making daily life activities more challenging. Motor functions, especially walking and balance, begin to deteriorate early in the disease and progress in parallel with cognitive decline. Dual-task performance, which refers to the ability to perform both motor and cognitive tasks simultaneously, significantly decreases in individuals with Alzheimer's disease. Current studies suggest that dual-task exercises can improve both cognitive and motor functions. In this context, treadmill-based dual-task training emerges as a promising approach to mitigate the effects of Alzheimer's disease. The study hypothesizes that treadmill-based dual-task training will have more positive effects on motor and cognitive parameters compared to treadmill exercise alone in individuals with Alzheimer's disease. The main research question of this study is whether treadmill-based dual-task exercise training, designed with progressively more challenging cognitive and motor tasks and tailored to the individual, results in significant improvements in motor and cognitive parameters, as well as daily living activities and dual-task performance, compared to a group that only undergoes treadmill exercise.
CONDITIONS
Official Title
Comparison of the Effectiveness of Treadmill-Based Walking and Dual-Task Walking Training in Alzheimer's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of Alzheimer's disease by a neurologist using NINCDS-ADRDA criteria
- Early or middle stage Alzheimer's disease based on Clinical Dementia Rating Scale
- Receiving treatment for Alzheimer's disease for at least 1 month
- Able to walk at least 400 meters in 6-Minute Walk Test
- Able to read and understand instructions in Turkish
You will not qualify if you...
- Diagnosis of Lewy body dementia, frontotemporal dementia, or other dementias
- Participation in a structured exercise program within 6 months before the study
- Presence of pulmonary, neurological, musculoskeletal, or rheumatological diseases hindering walking
- Unstable medical conditions like uncontrolled diabetes or hypertension
- Visual or hearing problems that impair communication
- Behavioral issues that prevent participation in exercise
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
İstanbul University-Cerrahpaşa
Istanbul, Turkey (Türkiye)
Actively Recruiting
Research Team
K
Kübra Nur Menengiç, MSc
CONTACT
İ
İpek Yeldan, Prof. Dr.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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