Actively Recruiting
Comparison of the Effectiveness of Two Psycho-physical Interventions: Mindfulness Based Relapse Prevention (MBRP) and Unguided Meditative Relaxation in Patients With Alcohol Use Disorder
Led by Centre Hospitalier Universitaire de Nīmes · Updated on 2025-08-21
168
Participants Needed
7
Research Sites
271 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Alcohol use disorder (AUD) is the second highest preventable cause of death in France. Only 3% of patients are prescribed approved drugs for reducing alcohol consumption or maintenance of abstinence. Increasing evidence supports the efficacy of psychotherapies such as cognitive and behavioral therapies (CBT) in AUD. However, some patients are resistant to CBT and the positive effects of CBT could wane over time, resulting in mid- and long-term relapses. Mindfulness practice is increasingly widespread in the United States and its efficacy in various fields appears very promising. The study investigators hypothesize that the Mindfulness Based Relapse Prevention (MBRP) program will be more efficient than a relaxation/meditation without guidance control program in AUD.
CONDITIONS
Official Title
Comparison of the Effectiveness of Two Psycho-physical Interventions: Mindfulness Based Relapse Prevention (MBRP) and Unguided Meditative Relaxation in Patients With Alcohol Use Disorder
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Have moderate to severe alcohol use disorder according to DSM 5 criteria
- Last drink consumed within 60 days before the pre-inclusion visit
- Have had at least one heavy drinking day during the last drinking period
You will not qualify if you...
- Severe depression (Beck Depression Inventory score greater than 30)
- Diagnosed with schizophrenic disorder
- Currently experiencing a manic or hypomanic episode
- Dementia or severe cognitive impairment preventing participation
- Insufficient understanding of French to complete questionnaires
- Pregnant or breastfeeding
- No social security coverage
- Receiving other mindfulness-based structured therapies
- Refusal to sign written consent
- Under safeguard of justice or state guardianship
AI-Screening
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Trial Site Locations
Total: 7 locations
1
Ssra Les Eumenides
Angers, France, 49100
Actively Recruiting
2
Hôpital Corentin-Celton
Issy-les-Moulineaux, France
Not Yet Recruiting
3
CHU de Nantes
Nantes, France
Actively Recruiting
4
CHU de Nimes
Nîmes, France
Actively Recruiting
5
Hopital Fernand Widal
Paris, France, 75010
Not Yet Recruiting
6
Hopital Des 4 Villes
Sèvres, France, 92310
Not Yet Recruiting
7
Hopital Paul Brousse
Villejuif, France
Not Yet Recruiting
Research Team
A
Amandine Luquiens
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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