Actively Recruiting

Phase Not Applicable
Age: 50Years - 75Years
All Genders
Healthy Volunteers
NCT06935812

Comparison of the Effects of Bimanual, Finger and VR Exercises in PwMCI

Led by Eastern Mediterranean University · Updated on 2025-07-09

106

Participants Needed

1

Research Sites

34 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Mild Cognitive Impairment (MCI) is defined as an impairment in a single cognitive function, usually memory, other than normal cognitive decline with age, that does not fulfil dementia criteria. Finger movements have been shown to stimulate the sensory-motor and cognitive parts of the cerebral cortex, as well as the supplementary motor area, Broca's area, premotor cortex, and prefrontal cortex, all of which contribute to movement skills. Asymmetrical hand and finger movements done concurrently were proven to improve cognitive processes and cerebral blood flow more than movements performed with one hand.

CONDITIONS

Official Title

Comparison of the Effects of Bimanual, Finger and VR Exercises in PwMCI

Who Can Participate

Age: 50Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants aged between 50 and 75 years
  • Diagnosed with mild cognitive impairment by a geriatrician according to DSM-5 criteria
  • Montreal Cognitive Assessment (MoCA) score between 13 and 26
  • Quick Mild Cognitive Impairment screen score between 48 and 67
  • Instrumental Activities of Daily Living Scale score of 6 or higher out of 8
  • Self-reported memory problem
  • Able to walk independently without using walking aids
Not Eligible

You will not qualify if you...

  • Musculoskeletal disorders causing balance or gait problems
  • Central or peripheral neurological diseases such as stroke, Parkinson's disease, or polyneuropathies
  • Use of psychiatric drugs affecting psychiatric disease or cognitive performance
  • Use of nonsteroidal anti-inflammatory drugs more than three times a week
  • Use of gingko biloba or antioxidant supplements like coenzyme Q10 or alpha-lipoic acid
  • Color blindness (daltonism)
  • Participation in any exercise program within the last 6 months

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Eastern Mediterranean University

Famagusta, Eyalet/Yerleşke, Cyprus, 99450

Actively Recruiting

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Research Team

B

Betül Fatma Bilgin, MSc PT

CONTACT

G

Gözde İyigün, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

4

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