Comparison of Effects for Lightening Shiners Among Different Treatments for Rhinitis in Children, Adolescents, and Adults

What this Trial Is About

Researchers are studying children, adolescents, and adults aged 6 to 65 years old who have moderate to severe allergic or non-allergic rhinitis to understand how different treatments affect the dark circles under the eyes known as shiners. These shiners are caused by fluid buildup due to nasal congestion common in rhinitis. The study aims to determine if treatments can reduce shiners and which treatment is most effective. Participants are randomly assigned to one of three treatment groups. One group receives oral antihistamine (Levocetirizine) alone. The second group receives a combination of intranasal corticosteroids (Mometasone Furoate) with oral Levocetirizine. The third group receives the same combination plus a one-week course of intranasal decongestant (Oxymetazoline). Digital images and questionnaires about quality of life related to rhinitis are collected before and after treatment at 1, 2, and 4 weeks. Throughout the study, researchers take standardized photos of the shiners and analyze their darkness and area using digital tools. Participants complete quality of life questionnaires appropriate for their age group. Data on patient history and medications are also collected. The main outcomes measured are changes in the darkness and size of the shiners at 1, 2, and 4 weeks after treatment. The study monitors how these changes relate to the effectiveness of the treatments for rhinitis.

Comparison of the Effects for Lightening the Shiners Among Different Treatments for Rhinitis