Comparison of the Efficacy of Celiac Plexus Blockade, Erector Spinae Compartment Blockade, and Intravenous Lidocaine Infusion Under Opioid-Free Anesthesia in Bariatric Surgery Patients

What this Trial Is About

Researchers are evaluating different non-opioid anesthesia methods to manage pain during bariatric surgery. The study compares three approaches: celiac plexus blockade, erector spinae plane (ESP) block, and intravenous lidocaine infusion, all performed under opioid-free anesthesia. This research aims to find which method provides better pain relief and fewer side effects, as opioid use often leads to issues like respiratory depression and nausea. The study is randomized and double-blinded to ensure reliable comparison between the methods. Participants are randomly assigned to one of three groups. The ESP group receives a block of the erector spinae compartment with ropivacaine before general anesthesia. The celiac plexus group receives a ropivacaine block during surgery under general anesthesia, causing no discomfort. The third group receives an intravenous lidocaine infusion instead of a regional block. All patients receive opioid-free anesthesia using ketamine, dexmedetomidine, and sevoflurane, followed by standard pain medications after surgery. During the study, pain levels are measured using the numeric rating scale (NRS) at multiple times within 24 hours after surgery. Patients also complete a quality of recovery questionnaire (QOR-15) the day after surgery, and the frequency of nausea and vomiting is tracked. The study focuses on how well patients recover and their pain management after bariatric surgery. Safety monitoring includes avoiding patients on medications that increase arrhythmia risk. The total follow-up involves assessments within the first postoperative day.

Comparison of the Efficacy of Celiac Plexus Blockade, ESP and Lidocaine Infusion Under OFA