Role of mesotherapy in musculoskeletal pain: opinions from the italian society of mesotherapy.
Massimo Mammucari, Antonio Gatti, Sergio Maggiori...
https://pubmed.ncbi.nlm.nih.gov/22654954Actively Recruiting
Led by Haydarpasa Numune Training and Research Hospital · Updated on 2026-02-18
50
Participants Needed
1
Research Sites
N/A
Total Duration
Researchers are evaluating the effectiveness of mesotherapy compared to extracorporeal shock wave therapy (ESWT) in treating patients with lateral epicondylitis, also known as tennis elbow. This randomized-controlled, single-blind study includes patients aged 18 to 65 years who have experienced elbow pain for at least six weeks. The study aims to determine whether mesotherapy is as effective as ESWT in relieving pain and improving function in this condition. Participants will be randomly assigned to one of two groups. Group 1 will receive mesotherapy injections consisting of lidocaine, pentoxifylline, thiocolchicoside, and meloxicam delivered intradermally using a fine needle at painful elbow points, with five sessions given once weekly. Group 2 will receive five weekly sessions of ESWT applied to the lateral epicondyle area with specified frequency, energy density, and pulse count. All participants are advised to use resting wrist splints and perform exercises. During the trial, participants will be assessed before treatment, 30 minutes after treatment completion, and again 12 weeks later. Evaluations include pain severity using the Visual Analogue Scale (VAS), functional impairment via the Patient-Rated Tennis Elbow Evaluation, and quality of life through the SF-12 Health Survey. Additional measurements include pressure-pain threshold and grip strength. Demographic and clinical data will be recorded, and safety and treatment effects will be monitored throughout the study duration.
CONDITIONS
Comparison of the Efficacy of Mesotherapy and Extracorporeal Shock Wave Therapy in Patients With Lateral Epicondylitis
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 5 weeks
Participants receive one of two treatments for lateral epicondylitis: Mesotherapy injections or Extracorporeal Shock Wave Therapy. Both treatments consist of 5 sessions given once every 7 days. Exercise and resting wrist splints are recommended for all participants.
5 weekly visits (in-person)
Duration - 7 weeks
Participants are assessed to evaluate treatment effects and recovery at 12 weeks after treatment completion.
1 follow-up visit (in-person)
Total: 1 location
1
Health Science University Haydarpasa Numune Research and Training Hospital, Istanbul, Uskudar 34668
Istanbul, Turkey (Türkiye)
Actively Recruiting
B
Berna Gunay, Medical doctor
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Massimo Mammucari, Antonio Gatti, Sergio Maggiori...
https://pubmed.ncbi.nlm.nih.gov/22654954