Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
ID07472296

Comparison of Erector Spinae Plane Block (ESPB) With Combined Superficial Parasternal Intercostal Plane Block (SPIPB) and Serratus Anterior Plane Block (SAPB) for Postoperative Sternotomy Pain in Cardiac Surgery Patients

Led by Uludag University · Updated on 2026-03-16

50

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating two regional anesthesia techniques to manage pain in patients undergoing cardiac surgery through sternotomy. The study compares the Erector Spinae Plane Block (ESPB) with a combination of the Superficial Parasternal Intercostal Plane Block (SPIPB) and Serratus Anterior Plane Block (SAPB) to see which provides better pain relief and recovery outcomes. This research focuses on adults aged 18 to 80 with specific physical health classifications undergoing elective surgery. Participants will be randomly assigned to one of two groups before general anesthesia. One group will receive a bilateral ultrasound-guided ESPB at the T4 or T5 vertebral level, where a local anesthetic called bupivacaine is injected. The other group will receive a combination of bilateral ultrasound-guided SPIPB and SAPB, also using bupivacaine, targeting different areas of the chest wall. Both techniques aim to reduce postoperative sternotomy pain. During the study, pain levels will be measured using a Visual Analog Scale at multiple time points up to 24 hours after surgery. Researchers will also assess extubation time, total opioid use, behavioral pain scores, and the time until the first additional pain medication is needed. Monitoring will continue for 24 hours post-surgery to evaluate recovery and pain management effectiveness. Participation includes nerve block procedures before surgery and follow-up assessments in the intensive care unit.

CONDITIONS

Brief Title

Comparison of Erector Spinae Plane Block (ESPB) With the Combination of Superficial Parasternal Intercostal Plane Block (SPIPB) and Serratus Anterior Plane Block (SAPB) in the Management of Postoperative Sternotomy Pain in Patients Undergoing Cardiac Surgery Via Sternotomy

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged between 18 and 80 years
  • Patients classified as American Society of Anesthesiologists (ASA) physical status I, II, or III
  • Patients scheduled for elective cardiac surgery via median sternotomy
  • Patients who have provided written informed consent
Not Eligible

You will not qualify if you...

  • Pregnancy or suspected pregnancy
  • Body Mass Index (BMI) greater than 35 kg/m²
  • Known allergy or hypersensitivity to local anesthetics such as bupivacaine
  • Suspected coagulopathy or bleeding disorders
  • Infection at the site of regional block injection
  • Severe liver or kidney failure
  • Severe neurological or psychiatric disorders
  • Emergency surgical procedures
  • Patients undergoing re-operation (redo-surgery)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Up to 24 hours post-surgery

Participants receive either the Erector Spinae Plane Block (ESPB) or a combination of Superficial Parasternal Intercostal Plane Block (SPIPB) and Serratus Anterior Plane Block (SAPB) prior to cardiac surgery via sternotomy.

1 visit on the day of surgery and monitoring for 24 hours postoperatively

Trial Site Locations

Total: 1 location

1

Bursa Uludag University Hospital

Bursa, Nilüfer, Turkey (Türkiye), 16235

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Published Research Related To This Trial

Randomized Controlled Trial of Ultrasound-Guided Parasternal Intercostal Nerve Block and Transversus Thoracis Muscle Plane Block for Postoperative Analgesia of Cardiac Surgical Patients.

Sachindra Yadav, Rajesh Raman, Rati Prabha...

https://pubmed.ncbi.nlm.nih.gov/39583527

Preemptive parasternal intercostal nerve block for patients undergoing off-pump coronary artery bypass grafting: a double-blind, randomized, controlled trial.

Mengmeng Zou, Wei Ruan, Jintao Liu...

https://pubmed.ncbi.nlm.nih.gov/37273884

Nociception level index-directed superficial parasternal intercostal plane block vs erector spinae plane block in open-heart surgery: a propensity matched non-inferiority clinical trial.

Cosmin Bălan, Cristian Boroş, Bianca Moroşanu...

https://pubmed.ncbi.nlm.nih.gov/39470954

Bilateral Parasternal Block and Bilateral Erector Spinae Plane Block Reduce Opioid Consumption in During Cardiac Surgery.

Paul Bousquet, François Labaste, Julie Gobin...

https://pubmed.ncbi.nlm.nih.gov/32843270

Erector spinae plane block versus its combination with superficial parasternal intercostal plane block for postoperative pain after cardiac surgery: a prospective, randomized, double-blind study.

Burhan Dost, Cengiz Kaya, Esra Turunc...

https://pubmed.ncbi.nlm.nih.gov/36114466