Comparing Erector Spinae Plane Block with Combined Parasternal and Serratus Anterior Plane Blocks for Pain Control After Cardiac Surgery via Sternotomy
Led by Uludag University · Updated on 2026-03-16
50
Participants Needed
1
Research Sites
4 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are evaluating two regional anesthesia techniques to manage pain in patients undergoing cardiac surgery through sternotomy. The study compares the Erector Spinae Plane Block ESPB with a combination of the Superficial Parasternal Intercostal Plane Block SPIPB and Serratus Anterior Plane Block SAPB to see which provides better pain relief and recovery outcomes. This research focuses on adults aged 18 to 80 with specific physical health classifications undergoing elective surgery.
Participants will be randomly assigned to one of two groups before general anesthesia. One group will receive a bilateral ultrasound-guided ESPB at the T4 or T5 vertebral level, where a local anesthetic called bupivacaine is injected. The other group will receive a combination of bilateral ultrasound-guided SPIPB and SAPB, also using bupivacaine, targeting different areas of the chest wall. Both techniques aim to reduce postoperative sternotomy pain.
During the study, pain levels will be measured using a Visual Analog Scale at multiple time points up to 24 hours after surgery. Researchers will also assess extubation time, total opioid use, behavioral pain scores, and the time until the first additional pain medication is needed. Monitoring will continue for 24 hours post-surgery to evaluate recovery and pain management effectiveness. Participation includes nerve block procedures before surgery and follow-up assessments in the intensive care unit.
CONDITIONS
Brief Title
Comparison of Erector Spinae Plane Block (ESPB) With the Combination of Superficial Parasternal Intercostal Plane Block (SPIPB) and Serratus Anterior Plane Block (SAPB) in the Management of Postoperative Sternotomy Pain in Patients Undergoing Cardiac Surgery Via Sternotomy
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Patients classified as American Society of Anesthesiologists (ASA) physical status I, II, or III
Patients scheduled for elective cardiac surgery via median sternotomy
Patients who have provided written informed consent
You will not qualify if you...
Pregnancy or suspected pregnancy
Body Mass Index (BMI) greater than 35 kg/m²
Known allergy or hypersensitivity to local anesthetics such as bupivacaine
Suspected coagulopathy or bleeding disorders
Infection at the site of regional block injection
Severe liver or kidney failure
Severe neurological or psychiatric disorders
Emergency surgical procedures
Patients undergoing re-operation (redo-surgery)
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Treatment
Duration - Up to 24 hours post-surgery
Participants receive either the Erector Spinae Plane Block (ESPB) or a combination of Superficial Parasternal Intercostal Plane Block (SPIPB) and Serratus Anterior Plane Block (SAPB) prior to cardiac surgery via sternotomy.
1 visit on the day of surgery and monitoring for 24 hours postoperatively
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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