Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT06183879

Comparison of Expandable and Fixed Size Cryoballoon for the Treatment of Paroxysmal Atrial Fibrillation

Led by University of Zagreb · Updated on 2024-05-28

150

Participants Needed

2

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to compare two different, market approved, cryoballoon devices for the treatment of paroxysmal atrial fibrillation (AF). The main aims of the study are: * to compare the efficacy of two ablation devices (acute and 1 year success rates) * to compare the procedural characteristics (procedure duration, fluoroscopy duration, ablation time * to compare the complication rates Participants who have indication for cryoballoon ablation of AF will be randomized in 1:1 fashion to older fixed size cryoballoon and newer expandable cryoballoon. Standard of care cryoballoon procedure will be performed alongside with standard postprocedural follow-up. • to compare the complication rates Participants who have indication for cryoballoon ablation of AF will be randomized in 1:1 fashion to older fixed size cryoballoon and newer expandable cryoballoon.

CONDITIONS

Official Title

Comparison of Expandable and Fixed Size Cryoballoon for the Treatment of Paroxysmal Atrial Fibrillation

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of paroxysmal atrial fibrillation
  • Scheduled for cryoballoon pulmonary vein isolation regardless of this study
Not Eligible

You will not qualify if you...

  • Unwilling to sign the informed consent
  • Left atrium size greater than 55 mm
  • Uncontrolled heart failure classified as NYHA III-IV
  • Presence of intracardiac thrombi

AI-Screening

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Trial Site Locations

Total: 2 locations

1

KB Dubrava

Zagreb, Please Select, Croatia, 10000

Actively Recruiting

2

KBC Zagreb

Zagreb, Croatia, 10000

Actively Recruiting

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Research Team

V

Vedran Velagic, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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