Study Comparing Flow-Controlled and Volume-Controlled Ventilation Effects on Lung Function During One-Lung Ventilation in Adults Undergoing Thoracic Surgery

What this Trial Is About

One-lung ventilation OLV is a common technique used during thoracic surgery but can negatively affect lung function and gas exchange. Researchers are studying and comparing two different ventilation methods, flow-controlled ventilation FCV and volume-controlled ventilation VCV, to see how they impact respiratory mechanics and oxygen levels during OLV in adult patients. This multicenter, prospective observational study aims to provide real-world evidence on these ventilation strategies to better understand their benefits and limitations. Patients undergoing thoracic surgery will receive either FCV or VCV as part of their usual care, without any changes made for the study. FCV is a newer method that precisely controls airflow during breathing cycles, while VCV is a commonly used conventional ventilation mode. Data on lung function, airway pressures, oxygenation, and gas exchange will be collected at specific times during both two-lung and one-lung ventilation phases during surgery. Participants will be monitored throughout their surgery with measurements of respiratory mechanics, blood oxygen levels, and other clinical parameters. The study will assess lung compliance, airway pressures, oxygenation capacity, and carbon dioxide elimination during OLV. This information will help improve understanding of lung-protective ventilation during thoracic surgery. The study includes adult patients aged 18 to 80 years and lasts for the duration of the surgical procedure with data collected intraoperatively.

Comparison of FCV and VCV in One-Lung Ventilation