Actively Recruiting

Phase Not Applicable
Age: 65Years +
All Genders
NCT07350044

Comparison of Femoral Nerve Block and Combined PENG Plus Femoral Nerve Block in Geriatric Hip Surgery

Led by Ankara City Hospital Bilkent · Updated on 2026-03-25

68

Participants Needed

1

Research Sites

19 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Hip fracture surgery in geriatric patients is frequently associated with severe perioperative pain, which may complicate positioning for spinal anesthesia and increase perioperative opioid requirements. Regional analgesic techniques are commonly used to improve patient comfort and reduce opioid consumption in this vulnerable population. The femoral nerve block is a well-established method for analgesia in hip surgery, while the pericapsular nerve group (PENG) block has emerged as a novel technique targeting articular branches of the hip joint with potential advantages in pain control. This prospective randomized controlled trial aims to compare the analgesic efficacy of femoral nerve block alone versus a combined pericapsular nerve group (PENG) plus femoral nerve block in geriatric patients undergoing hip fracture surgery under spinal anesthesia. The primary outcomes include perioperative pain intensity, opioid consumption within the first 24 hours postoperatively, and the need for additional analgesia during positioning for spinal anesthesia. Secondary outcomes include spinal anesthesia procedure duration, time to sensory block onset, time to first postoperative opioid requirement, and perioperative hemodynamic parameters. The results of this study are expected to clarify whether the addition of the PENG block to femoral nerve block provides superior perioperative analgesia and improved patient comfort compared with femoral nerve block alone in geriatric hip fracture surgery.

CONDITIONS

Official Title

Comparison of Femoral Nerve Block and Combined PENG Plus Femoral Nerve Block in Geriatric Hip Surgery

Who Can Participate

Age: 65Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 65 years and older
  • Scheduled for surgery due to hip fracture
  • American Society of Anesthesiologists (ASA) physical status I-III
  • Body mass index between 18 and 40 kg/m²
  • Preoperative fasting duration of approximately 8 hours
  • Planned spinal anesthesia
  • Ability to provide written informed consent
Not Eligible

You will not qualify if you...

  • Age below 65 years
  • Refusal to participate in the study
  • Severe cognitive impairment, dementia, or Alzheimer's disease
  • ASA physical status IV or higher
  • Body mass index greater than 40 kg/m²
  • Failed spinal anesthesia or conversion to general anesthesia
  • Revision hip surgery
  • Multiple trauma patients
  • Old hip fractures (greater than 3 weeks)
  • Active malignancy receiving chemotherapy or radiotherapy
  • Active infection requiring antibiotic treatment (except prophylaxis)
  • Contraindications to regional anesthesia techniques
  • Chronic steroid or immunosuppressive therapy
  • Use of anti-inflammatory drugs
  • Non-fasted patients
  • Allergy or intolerance to local anesthetics, paracetamol, tramadol, or other opioids

AI-Screening

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Trial Site Locations

Total: 1 location

1

Ankara Bilkent City Hospital

Ankara, Turkey (Türkiye)

Actively Recruiting

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Research Team

S

Sündüz İlayda Yıldız Akça

CONTACT

S

Semih Başkan

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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